Keys to the genome: Unlocking the package with 'pioneer transcription factors'
Scientists at the Montreal Clinical Research Institute have discovered the molecular mechanisms responsible for opening up the human genome and expressing new genes.
Scientists at the Montreal Clinical Research Institute have discovered the molecular mechanisms responsible for opening up the human genome and expressing new genes.
Molecular & Computational biology
Apr 11, 2024
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Researchers from Carnegie Mellon University's School of Computer Science have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing ...
Cell & Microbiology
Apr 9, 2024
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140
The Hare Research Group at the Department of Environmental and Biological Sciences, University of Eastern Finland, has published a chromosomally assembled reference genome for the European brown hare. Reference genomes represent ...
Plants & Animals
Mar 20, 2024
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The Human Genome Project generated the first sequence of the human genome, revealing a kind of blueprint of human biology. Two decades later, the field of gene regulatory networks describes a complex system where thousands ...
Biotechnology
Mar 14, 2024
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"Random DNA" is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular ...
Evolution
Mar 6, 2024
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13
Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium ...
Molecular & Computational biology
Mar 1, 2024
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Writing a commentary in the 50th anniversary issue of Cell, Fu Qiaomei and E. Andrew Bennett, both of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, explored the ...
Evolution
Feb 29, 2024
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187
A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys, finds a new study led by researchers at NYU Grossman School of Medicine.
Evolution
Feb 28, 2024
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The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job of knocking out genes to cure hereditary disease. But it's still not possible to insert whole genes ...
Biotechnology
Feb 20, 2024
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148
An international research team has discovered that a previously overlooked repetitive DNA element known as Long Interspersed Nuclear Element (L1) helps maintain neural progenitor cells, and thus plays an important role in ...
Cell & Microbiology
Feb 14, 2024
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29