News tagged with human genome
Researchers reveal an RNA modification influences thousands of genes
Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics ...
May 17, 2012 |
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Enzyme corrects more than one million faults in DNA replication
Scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh have discovered an enzyme that corrects the most common mistake in mammalian DNA.
May 10, 2012 |
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Scientists create first 3-D map of human genome
(PhysOrg.com) -- For the first time, scientists have developed a method for generating accurate three-dimensional models of the entire DNA strand of a cell, known as a genome.
Jan 04, 2012 |
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Entire genome of extinct human decoded from fossil
(PhysOrg.com) -- In 2010, Svante Pääbo and his colleagues presented a draft version of the genome from a small fragment of a human finger bone discovered in Denisova Cave in southern Siberia. The ...
Feb 07, 2012 |
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Study dusts sugar coating off little-known regulation in cells
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Apr 16, 2012 |
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A new optical microscopy approach opens the door to better observations in molecular biology
Researchers from the Institut Pasteur and CNRS have set up a new optical microscopy approach that combines two recent imaging techniques in order to visualize molecular assemblies without affecting their biological ...
May 17, 2012 |
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'Dark matter' of the genome revealed through analysis of 29 mammals
An international team of researchers has discovered the vast majority of the so-called "dark matter" in the human genome, by means of a sweeping comparison of 29 mammalian genomes. The team, led by scientists from the Broad ...
Oct 12, 2011 |
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Improved adult-derived human stem cells have fewer genetic changes than expected
A team of researchers from Johns Hopkins University and the National Human Genome Research Institute has evaluated the whole genomic sequence of stem cells derived from human bone marrow cellsso-called induced pluripotent ...
May 01, 2012 |
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Control of gene expression: Histone occupancy in your genome
When stretched out, the genome of a single human cell can reach six feet. To package it all into a tiny nucleus, the DNA strand is tightly wrapped around a core of histone proteins in repeating unitseach ...
Apr 30, 2012 |
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Mouse genetic blueprint developed
Researchers have developed a valuable mouse genetic blueprint that will accelerate future research and understanding of human genetics. The international team, led by researchers at the Wellcome Trust Sanger ...
Sep 14, 2011 |
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Neanderthals may have interbred with humans twice
(PhysOrg.com) -- Extinct human species such as Neanderthals may still be with us, at least in our DNA, and this may help explain why they disappeared from the fossil record around 30,000 years ago.
New algorithm provides new insights into evolutionary exodus out of Africa
Researchers have probed deeper into human evolution by developing an elegant new technique to analyse whole genomes from different populations. One key finding from the Wellcome Trust Sanger Institute's study is that African ...
Jul 13, 2011 |
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lobSTR algorithm rolls DNA fingerprinting into 21st century
As any crime show buff can tell you, DNA evidence identifies a victim's remains, fingers the guilty, and sets the innocent free. But in reality, the processing of forensic DNA evidence takes much longer than a 60-minute primetime ...
Apr 27, 2012 |
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Breeding with Neanderthals appears to have helped early humans fight disease
(PhysOrg.com) -- Following up on evidence that Homo Sapiens and Neanderthals mated and produced offspring, following the sequencing of the Neanderthal genome last year, Peter Parham, professor of microbiology ...
Genetic sequencing alone doesn't offer a true picture of human disease
Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand ...
Jan 23, 2011 |
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Human genome
The human genome is the genome of Homo sapiens, which is stored on 23 chromosome pairs. Twenty-two of these are autosomal chromosome pairs, while the remaining pair is sex-determining. The haploid human genome occupies a total of just over 3 billion DNA base pairs. The Human Genome Project (HGP) produced a reference sequence of the euchromatic human genome, which is used worldwide in biomedical sciences.
The haploid human genome contains an estimated 20,000–25,000 protein-coding genes, far fewer than had been expected before its sequencing. In fact, only about 1.5% of the genome codes for proteins, while the rest consists of RNA genes, regulatory sequences, introns and (controversially) "junk" DNA.
For more information about Human genome, read the full article at
Wikipedia.
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