Pulling the strings of our genetic puppetmasters: Engineers gain control of gene activity
Duke researchers have developed a new method to precisely control when genes are turned on and active.
How RNA machinery navigates our genomic obstacle course
Once upon a time, scientists thought RNA polymerase—the molecule that kicks off protein synthesis by transcribing DNA into RNA—worked like a wind-up toy: Set it down at a start site in our DNA and it ...
Viral proteins may regulate human embryonic development
A fertilized human egg may seem like the ultimate blank slate. But within days of fertilization, the growing mass of cells activates not only human genes but also viral DNA lingering in the human genome from ...
Genetic markers for fetal overgrowth syndrome discovered
Humans and cattle share a similar epigenetic fetal overgrowth disorder that occurs more commonly following assisted reproduction procedures. In humans, this disorder is called Beckwith-Wiedemann syndrome ...
Chromosome-folding theory shows promise
Human chromosomes are much bigger and more complex than proteins, but like proteins, they appear to fold and unfold in an orderly process as they carry out their functions in cells.