Researchers use base editing to probe blood cell biology
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Cell & Microbiology
May 3, 2023
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11
By comparing the genetic blueprints of an array of animals, scientists are gaining new insights into our own species and all we share with other creatures.
Molecular & Computational biology
Apr 30, 2023
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27
Hundreds of scientific studies have been conducted over the years to find the genes underlying common human traits, from eye color to intelligence and physical and mental illnesses.
Evolution
Apr 27, 2023
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15
The completion of the full "telomere-to-telomere" (T2T) human genome last year emphasized that genome sequences that were previously thought to be "complete" were not, in fact, complete at all.
Molecular & Computational biology
Apr 5, 2023
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69
DNA and associated proteins in active regions of the genome are condensed but behave like a viscous liquid at the molecular level. This finding greatly increases our understanding of the physical nature of expressed genome ...
Cell & Microbiology
Apr 5, 2023
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195
With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. Evolutionary geneticist Asher Cutter proposes that ...
Evolution
Mar 28, 2023
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119
The community of microbes living in and on our bodies may be acting as a reservoir for antibiotic resistance, according to new research from the Earlham Institute and Quadram Institute in Norwich. The work is published in ...
Cell & Microbiology
Mar 27, 2023
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57
Conventional analysis of cellular lipids mainly involves radiometric analysis and mass spectrometry of cell extracts collected in large quantities. This method is time-consuming and labor-intensive and burdensome when analyzing ...
Biotechnology
Mar 27, 2023
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19
A major puzzle of biology is that while the human genome contains roughly 20,000 genes, many comparatively primitive organisms—including the universally-studied worm C. elegans—have almost the same number of genes.
Biotechnology
Mar 23, 2023
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133
Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other diseases, by ensuring that synthetic ...
Biotechnology
Mar 16, 2023
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14