News tagged with homologous recombination
On the move for repair
Scientists from the Friedrich Miescher Institute for Biomedical Research have elucidated mechanisms that control DNA movement in the nucleus. They found that DNA with double-strand breaks moves more than undamaged ...
Apr 17, 2012 |
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Safeguarding genome integrity through extraordinary DNA repair
(PhysOrg.com) -- DNA is under constant attack, from internal factors like free radicals and external ones like ionizing radiation. About 10 double-strand breaks – the kind that snap both backbones of ...
Apr 19, 2011 |
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Researchers develop process for 'surgical' genetic changes
Research led by scientists at Iowa State University's Plant Sciences Institute has resulted in a process that will make genetic changes in plant genes much more efficient, practical and safe.
Jul 20, 2009 |
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Search results for homologous recombination
FANCM plays key role in inheritance
Scientists of KIT and the University of Birmingham have identified relevant new functions of a gene that plays a crucial role in Fanconi anemia, a life-threatening disease.
Apr 30, 2012 |
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Precise molecular surgery in the plant genome
Crop plants have always been adapted to the needs of man by breeding for them to carry more fruit, survive droughts, or resist pests. Green biotechnology now adds new tools to the classical breeding methods ...
Apr 24, 2012 |
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Pinpointing how antibiotics work
Penicillin and other antibiotics have revolutionized medicine, turning once-deadly diseases into easily treatable ailments. However, while antibiotics have been in use for more than 70 years, the exact mechanism ...
Apr 20, 2012 |
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Cure of ADPKD by selection for spontaneous genetic repair events in Pkd1-mutated iPS cells
A research group including Kyoto University researchers demonstrates that mouse iPS cells, in which genetic correction occurs spontaneously through mitotic recombination, is selectable from the population of genetically mutated ...
Feb 10, 2012 |
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Study shows how DNA finds its match
It's been more than 50 years since James Watson and Francis Crick showed that DNA is a double helix of two strands that complement each other. But how does a short piece of DNA find its match, out of the millions ...
Feb 08, 2012 |
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Unique E. coli protein may be not after all
A bacterial protein recently thought to be a unique mechanism for utilizing iron may not be after all. Researchers from the University of Georgia, the Fellowship for Interpretation of Genomes, the University of Oklahoma and ...
Jan 03, 2012 |
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Study reveals new role for RNA interference during chromosomal replication
At the same time that a cell's DNA gets duplicated, a third of it gets super-compacted into repetitive clumps called heterochromatin. This dense packing serves to repress or "silence" the DNA sequences within -- which could ...
Oct 16, 2011 |
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Insect virus holds the key to safer stem cell therapy
The future of regenerative medicine lies in harnessing the potential of the human body to renew and repair itself. Now, scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world’s ...
Jul 29, 2011 |
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A knockout resource for mouse genetics
An international consortium of researchers report today in Nature that they have knocked out almost 40 per cent of the genes in the mouse genome. The completed resource will power studies of gene activity in models of hum ...
Jun 15, 2011 |
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Editing scrambled genes in human stem cells may help realize the promise of stem cell-gene therapy
In principle, genetic engineering is simple, but in practice, replacing a faulty gene with a healthy copy is anything but. Using mutated versions of the lamin A gene as an example to demonstrate the versatility of their virus-based ...
May 19, 2011 |
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List of search results for homologous recombination
