We tend to think of the human body as operating out of a sense-and-respond paradigm. For example, you eat sugar, the pancreas senses the intake, and it responds by releasing the hormone insulin to keep the body's glucose ...
Biochemistry
Mar 1, 2022
1
104
Temperature and dissolved oxygen (DO) can affect a series of physiological and biochemical responses and drive the expression of regulatory genes. When water temperature increases, the solubility of oxygen decreases, leading ...
Plants & Animals
Jan 21, 2022
0
18
G protein-coupled receptors (GPCRs) play essential roles in cell signal transduction and serve as important therapeutic targets for a large number of diseases. Upon binding to extracellular agonists, GPCRs stimulate various ...
Cell & Microbiology
Mar 19, 2020
0
127
Despite humanity's best efforts to eradicate malaria, the disease struck more than 200 million people in 2017, according to the World Health Organization. Worse yet, the parasite that causes malaria is developing resistance ...
Biochemistry
Oct 16, 2019
0
46
Working with bacteria, a multidisciplinary team at the University of California San Diego has provided new insight into a longstanding question in science: What are the underlying mechanisms that control the size of cells?
Cell & Microbiology
May 17, 2019
1
97
Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins. ...
Cell & Microbiology
May 20, 2016
0
6
Cellular repair systems can dissolve aggregated proteins and now Heidelberg researchers have successfully decoded the fundamental mechanism that is key to dissolving these protein aggregates in human cells. Their in-vitro ...
Cell & Microbiology
Aug 12, 2015
1
99
Those bacteria that require iron walk a tightrope. Iron is essential for their growth, but too much iron can damage DNA and enzymes through oxidation. Therefore, bacteria have machinery to maintain their intracellular iron ...
Cell & Microbiology
Jul 7, 2015
0
22
Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases. ...
Cell & Microbiology
Sep 22, 2013
0
0
Virginia Commonwealth University researchers studying a key molecular player called Hsp70 that is responsible for protein homeostasis have uncovered how it binds together with another molecule responsible for intracellular ...
Cell & Microbiology
May 30, 2013
0
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