News tagged with histone proteins

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Dissecting the brain's primary developmental engine

(Phys.org) —Last month, researchers reported the creation of the first primitive brain-like structures made from human stem cells. To create the complex morphology of these cerebral organoids, cells within a proliferating neuroectodermal layer were converted int ...

Sep 18, 2013 report
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Histone exchanger comes into focus

The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, ...

Sep 16, 2013
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A skeleton for chromosomes

Researchers at the IMP Vienna discovered that cohesin stabilizes DNA. Jan-Michael Peters and his team at the Research Institute of Molecular Pathology (IMP) found that the structure of Chromosomes is supported ...

Aug 26, 2013
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Unspooling DNA from nucleosomal disks

The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism that allows chromosomal ...

May 23, 2013
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