Mapping how cell types and tissues develop

Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific ...

Computer simulations animate in atomic detail how DNA opens

Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA ...

How epigenetic switches control gene expression

Scientists at Tokyo Institute of Technology have deciphered how to quantitatively assess the effects of specific epigenetic changes on the rate of transcription by developing a mathematical model. Using their method, they ...

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