News tagged with histone deacetylases
Effective inducing systems of hepatic differentiation from bone marrow mesenchymal stem cells
Mesenchymal stem cells (MSCs) are multipotent non-hematopoietic cells capable of differentiating into hepatocytes. Valproic acid (VPA), a histone deacetylase inhibitor, has recently exhibited profound therapeutic activity ...
Medicine & Health / Medical research
Jul 30, 2010 |
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Is hepatic differentiation of embryonic stem cells induced by valproic acid and cytokines?
Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. ...
Medicine & Health / Medical research
Nov 18, 2009 |
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Mechanism for potential Friedreich's ataxia drug uncovered
Using clever chemistry, a Scripps Research team has pinpointed the enzyme target of a drug group that stops the progression of the devastating disease Friedreich's ataxia in mice and may do the same for humans. The findings, ...
Sep 25, 2009 |
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Lipid involved with gene regulation uncovered
(PhysOrg.com) -- Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that ...
Sep 08, 2009 |
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Lipid involved with gene regulation uncovered
Virginia Commonwealth University School of Medicine researchers have discovered a new role for the bioactive lipid messenger, sphingosine-1-phosphate, or S1P, that is abundant in our blood - a finding that could lead to a ...
Sep 04, 2009 |
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