Related topics: drug

Scientists create vaccine against heroin high

Researchers at The Scripps Research Institute have developed a highly successful vaccine against a heroin high and have proven its therapeutic potential in animal models.

Senators target Internet narcotics

(AP) -- Two U.S. senators said Sunday they will ask federal authorities to crack down on a secretive narcotics market operated on the Internet with anonymous sales and untraceable currency.

New discovery helps authorities pinpoint origin of heroin

Researchers at Florida International University's International Forensic Research Institute (IFRI) have zeroed in on a unique component of heroin that could pinpoint where it was grown, giving authorities a new tool to potentially ...

Five things to know about Bayer and Monsanto

The second cancer victim in a year to win a surprise victory against US pesticide maker Monsanto raises the prospect of a flood of similar lawsuits, potentially leaving the firm's new German owner Bayer with a major case ...

Antidote to opioid drug overdoses could become more accessible

Over the past 15 years, deaths caused by heroin and prescription opioid overdoses have quadrupled despite the existence of a highly effective antidote. The cover story in Chemical & Engineering News (C&EN), the weekly newsmagazine ...

Cocaine and heroin harm placenta

Cocaine and heroin increase permeability of the placenta. Researchers writing in BioMed Central's open access journal Reproductive Biology and Endocrinology have shown that exposure to the drugs causes an increase in the ...

Heroin

Heroin (diacetylmorphine (INN)), also known as diamorphine (BAN), or, especially in older literature, as morphine diacetate, is an opioid analgesic synthesized from morphine, a derivative of the opium poppy. When used in medicine it is typically used to treat severe pain, such as that resulting from a heart attack. It is the 3,6-diacetyl ester of morphine, and functions as a morphine prodrug (meaning that it is metabolically converted to morphine inside the body). The white crystalline form considered "pure heroin" is usually the hydrochloride salt, diacetylmorphine hydrochloride. When heroin is supplied illegally, though, it is often adulterated to a freebase form, dulling the sheen and consistency to a matte white powder. As of 2004, roughly 87% of the world supply of opium and its derivatives, including heroin, was thought to be produced in Afghanistan. However, production in Mexico has risen six-fold from 2007 to 2011, changing that percentage and placing Mexico as the second largest opium producer in the world.

As with other opioids, diacetylmorphine is used as both an analgesic and a recreational drug. Frequent and regular administration is associated with tolerance and physical dependence, which may develop into addiction. Internationally, diacetylmorphine is controlled under Schedules I and IV of the Single Convention on Narcotic Drugs. It is illegal to manufacture, possess, or sell diacetylmorphine without a license in almost every country.

Under the chemical names diamorphine and diacetylmorphine, heroin is a legally prescribed controlled drug in the United Kingdom, and is supplied in tablet or injectable form for the same indications as morphine is, often being preferred over morphine due to its lower side effect profile. It is also available for prescription to long-term users in the Netherlands, United Kingdom, Switzerland, Germany and Denmark alongside psycho-social care, and a similar programme is being campaigned for by liberal political parties in Norway.

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