(Phys.org) —Viruses are masters of minimalist design. With only a simple genome and a handful of proteins, a virus can hijack much more sophisticated cells and mimic many of the intra- and inter-cellular machinery built ...
Biochemistry
Jun 14, 2013
0
0
Researchers have cracked a code that governs infections by a major group of viruses including the common cold and polio.
Cell & Microbiology
Feb 4, 2015
15
632
Sarbecoviruses have crossed into humans twice in the last decade, leading to the deadly SARS-CoV-1 outbreak in 2002-04 and the current COVID-19 pandemic, caused by the SARS-CoV-2 virus. A new Oxford University study, published ...
Evolution
Sep 3, 2021
2
2050
(Phys.org) —Theiler's Disease is one of the most common causes of equine hepatitis. Death rates in horses that develop symptoms range between 50 and 90 percent. Although veterinarians have known about Theiler's Disease ...
(PhysOrg.com) -- Researchers at the University of California, Berkeley, have for the first time captured elusive nanoscale movements of ribosomes at work, shedding light on how these cellular factories take in genetic instructions ...
Cell & Microbiology
Aug 20, 2009
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0
The 2020 Nobel Prize for physics is being announced Tuesday, an award that has in the past honored discoveries about the tiniest of particles and the vast mysteries of outer space.
General Physics
Oct 6, 2020
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197
Mucosal epithelia do not have any receptors on the outer membrane for the absorption of viruses like hepatitis C, herpes, the adenovirus or polio, and are thus well-protected against pathogenic germs. However, certain viruses, ...
Cell & Microbiology
Jul 21, 2011
0
0
Scientists at The Scripps Research Institute (TSRI) have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural ...
Cell & Microbiology
Nov 28, 2013
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0
Researchers at the National Institutes of Health have discovered a biological pathway that the novel coronavirus appears to use to hijack and exit cells as it spreads through the body. A better understanding of this important ...
Cell & Microbiology
Oct 29, 2020
0
381
Viral infection is one of the leading medical challenges of the 21st Century, ranging from the Hepatitis C Virus (HCV) epidemic affecting 3% of the global population, to recent outbreaks of West Nile, Zika, and Ebola viruses.
Biochemistry
Oct 11, 2016
0
2
Hepatitis C is an infectious disease affecting the liver, caused by the hepatitis C virus (HCV). The infection is often asymptomatic, but once established, chronic infection can progress to scarring of the liver (fibrosis), and advanced scarring (cirrhosis) which is generally apparent after many years. In some cases, those with cirrhosis will go on to develop liver failure or other complications of cirrhosis, including liver cancer.
The hepatitis C virus (HCV) is spread by blood-to-blood contact. Most people have few, if any symptoms after the initial infection, yet the virus persists in the liver in about 85% of those infected. Persistent infection can be treated with medication, peginterferon and ribavirin being the standard-of-care therapy. Only 51% are cured overall. Those who develop cirrhosis or liver cancer may require a liver transplant, and the virus universally recurs after transplantation.
An estimated 270-300 million people worldwide are infected with hepatitis C. Hepatitis C is a strictly human disease. It cannot be contracted from or given to any animal. Chimpanzees can be infected with the virus in the laboratory, but do not develop the disease, which has made research more difficult. No vaccine against hepatitis C is available. The existence of hepatitis C (originally "non-A non-B hepatitis") was postulated in the 1970s and proved conclusively in 1989. It is one of five known hepatitis viruses: A, B, C, D, and E.
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