News tagged with hematopoietic stem cells
Artificial blood developed for the battlefield
(PhysOrg.com) -- US scientists working for the experimental arm of the Pentagon have developed artificial blood for use in transfusions for wounded soldiers in battlefields. The blood cells are said to be ...
Medicine & Health / Medical research
Jul 13, 2010 |
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Scientists successfully reprogram blood cells
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -preventing or reducing organ and central nervous system damage ...
Nov 09, 2009 |
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Researchers parse the origins of hematopoietic stem cells
Researchers at the University of California, San Diego School of Medicine have identified a gene and a novel signaling pathway, both critical for making the first hematopoietic stem cells (HSCs) in developing ...
Jun 08, 2011 |
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Researchers develop platform to monitor hematopoietic stem cells
A Canadian research team has developed an automated microfluidic cell culture platform to monitor the growth, survival and responses of hundreds of hematopoietic stem cells (HSCs) at the single cell level.
May 22, 2011 |
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How long do stem cells live?
When patients receive a bone marrow transplant, they are getting a new population of hematopoietic stem cells. Fresh stem cells are needed when a patient is low on red blood cells, as in anemia, or white blood cells, which ...
Medicine & Health / Medical research
Mar 01, 2011 |
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Stem cell discovery could lead to improved bone marrow transplants
Researchers at the University of California, Santa Cruz, have identified a key molecule for establishing blood stem cells in their niche within the bone marrow. The findings, reported in the January issue of Cell Stem Ce ...
Jan 06, 2011 |
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Inhibiting cell signaling pathway may improve bone marrow transplant success rate
Identification of a molecular communications pathway that influences the mobilization of hematopoietic (blood) stem cells could lead to targeted therapies for improving bone marrow transplant success rates.
Medicine & Health / Medical research
Sep 26, 2010 |
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Study confirms location of stem cells near cartilage-rich regions in bones
Working with mice, a team of researchers has pinpointed the location of bone generating stem cells in the spine, at the ends of shins, and in other bones. The team also has identified factors that control the stem cells' ...
Medicine & Health / Medical research
Apr 26, 2010 |
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Biologists image birth of blood-forming stem cells in embryo (w/ Video)
Biologists at UC San Diego have identified the specific region in vertebrates where adult blood stem cells arise during embryonic development.
Feb 14, 2010 |
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Discovery of a mechanism controlling the fate of hematopoietic stem cells
(PhysOrg.com) -- Hematopoietic stem cells are capable of manufacturing all types of blood cells. But which factors influence the production of a specific type of cell? Until now, it was thought that this was ...
Jul 30, 2009 |
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Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps, according to new ...
Jul 27, 2009 |
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Researchers uncover signaling pathway that regulates movement of blood-forming stem cells
Researchers at the Keck School of Medicine of the University of Southern California (USC) have identified a signaling pathway that helps regulate the movement of blood-forming stem cells in the body—a finding that provides ...
Medicine & Health / Medical research
Mar 25, 2009 |
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Prostate cancer spreads to bones by overtaking the home of blood stem cells
Like bad neighbors who decide to go wreck another community, prostate and breast cancer usually recur in the bone, according to a new University of Michigan study.
Mar 23, 2011 |
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Unappreciated dynamism of blood cell production
The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in the Journal of Experimental Medicine.
Medicine & Health / Medical research
Feb 07, 2011 |
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Poor breast cancer prognosis associated with presence of circulating tumor, cancer stem cells
Metastatic breast cancer patients whose blood contains circulating tumor cells (CTCs) before or after treatment with high-dose chemotherapy and blood stem cell transplant have shorter survival periods, according to a new ...
Dec 10, 2010 |
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Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are multipotent stem cells that give rise to all the blood cell types including myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T-cells, B-cells, NK-cells). The definition of hematopoietic stem cells has undergone considerable revision in the last two decades. The hematopoietic tissue contains cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. Recently, long-term transplantation experiments point toward a clonal diversity model of hematopoietic stem cells. Here, the HSC compartment consists of a fixed number of different types of HSC, each with epigenetically preprogrammed behavior. This contradicts older models of HSC behavior, which postulated a single type of HSC that can be continuously molded into different subtypes of HSCs. HSCs constitute 1:10.000 of cells in myeloid tissue.
For more information about Hematopoietic stem cell, read the full article at
Wikipedia.
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