A study from Patrick Matthias and his group at the FMI challenges a widely accepted model on how epigenome dynamics control the differentiation of hematopoietic cells. The plasticity of pluripotent stem cells was thought ...
Cell & Microbiology
Oct 20, 2015
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Researchers at the Stanford University School of Medicine have discovered the stem cell in mice that gives rise to bone, cartilage and a key part of bone marrow called the stroma.
Cell & Microbiology
Jan 15, 2015
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Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced ...
Cell & Microbiology
Nov 6, 2014
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When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete ...
Cell & Microbiology
May 21, 2013
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Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
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Not all adult stem cells are created equal. Some are busy regenerating worn out or damaged tissues, while their quieter brethren serve as a strategic back-up crew that only steps in when demand shoots up. Now, researchers ...
Cell & Microbiology
Jul 19, 2012
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Researchers at the University of California, San Diego School of Medicine have identified a gene and a novel signaling pathway, both critical for making the first hematopoietic stem cells (HSCs) in developing vertebrate embryos. ...
Cell & Microbiology
Jun 8, 2011
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A Canadian research team has developed an automated microfluidic cell culture platform to monitor the growth, survival and responses of hundreds of hematopoietic stem cells (HSCs) at the single cell level.
Cell & Microbiology
May 22, 2011
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Researchers at the University of California, Santa Cruz, have identified a key molecule for establishing blood stem cells in their niche within the bone marrow. The findings, reported in the January issue of Cell Stem Cell, ...
Cell & Microbiology
Jan 6, 2011
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French researchers from CNRS and the Universite Paul Sabatier have demonstrated the existence, in adipose tissue, of stem cells similar to those found in bone marrow. These cells are capable of differentiating into mast cells, ...
Cell & Microbiology
Nov 26, 2010
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