Scientists have combined laser 3D printing technology and an alternate soaking process to construct complex 3D structures that mimic bone microstructure. This is the first demonstration of this fabrication method, and it ...
Biochemistry
Feb 12, 2024
0
64
Blood cells make up the majority of cells in the human body. They perform critical functions and their dysfunction is implicated in many important human diseases, from anemias to blood cancers like leukemia. The many types ...
Cell & Microbiology
Jan 31, 2024
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53
A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, providing a valuable new insight in the effort to create patient-derived blood stem cells ...
Cell & Microbiology
Dec 19, 2023
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96
A research team led by Professor Megumu K. Saito (Department of Clinical Application) examined the dynamic transcriptional and epigenetic landscape during definitive hematopoiesis and revealed the non-redundant roles of ZEB2 ...
Cell & Microbiology
Oct 18, 2023
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10
A readily available, inexpensive, small molecule drug can improve the fitness of hematopoietic stem and progenitor cells (HSPCs) that are modified outside the body, potentially improving the success of procedures such as ...
Cell & Microbiology
Sep 27, 2023
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1
Myelotoxicity is the primary dose-limiting effect of the commonly used chemotherapeutic agent 5-fluorouracil (5-FU), which may endanger the life of the patient. Ribosome biogenesis is a key pathway regulating hematopoietic ...
Cell & Microbiology
Aug 8, 2023
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5
In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept ...
Biotechnology
Jul 27, 2023
0
69
In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells ...
Cell & Microbiology
Mar 21, 2023
0
78
Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type. HSC transplants can be used to treat conditions where bone marrow is damaged and ...
Cell & Microbiology
Feb 27, 2023
0
48
The body is constantly replenishing the blood with new red and white blood cells thanks to a small but important group of cells called hematopoietic stem cells (HSCs). Now, researchers at the Broad Institute of MIT Harvard, ...
Cell & Microbiology
Feb 17, 2023
0
20
