News tagged with heat shock
Heat shock protein drives yeast evolution
Whitehead Institute researchers have determined that heat shock protein 90 (Hsp90) can create heritable traits in brewer's yeast (Saccharomyces cerevisiae) by affecting a large portion of the yeast genome. The finding has le ...
Dec 23, 2010 |
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Study uncovers how DNA unfolds for transcription
(PhysOrg.com) -- The human genome contains some 3 billion base pairs that are tightly compacted into the nucleus of each cell. If a DNA strand were the thickness of a human hair, the entire human genome would ...
Jan 17, 2012 |
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A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011 |
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Listeria clever at finding its way into bloodstream, causing sickness
Pathogenic listeria tricks intestinal cells into helping it pass through those cells to make people ill, and, if that doesn't work, the bacteria simply goes around the cells, according to a Purdue University ...
Medicine & Health / Medical research
Oct 25, 2010 |
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German researchers demonstrate rocking movement in the anti-stress protein Hsp90
The protein Hsp90 plays a significant role in the survival of cells that are exposed to stress. Researchers at the Technische Universitaet Muenchen (TUM) uncovered this protein's mode of operation some time ...
Aug 23, 2010 |
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New way to fight drug-resistant fungal infections discovered
(PhysOrg.com) -- The secret to fighting often lethal drug resistant fungal infections is to knock out the bug's molecular chaperone, according to U of T researchers.
Jul 31, 2009 |
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Weightlessness weighs heavy on genes -- a fly's perspective
On Earth all biology is subjected to gravity. Some biological systems require gravity for correct orientation (geotropism: plants grow up, roots grow down). In the absence of gravity even human biology is affected: astronauts ...
Jan 31, 2012 |
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Researchers study Terahertz radiation's impact on cellular function and gene expression
Terahertz (THz) technologies show promise for myriad medical, military, security, and research applications ranging from the detection of cancer to airport security systems to shipment inspection to spectroscopy. Relatively ...
Sep 13, 2011 |
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Mechanism for stress-induced epigenetic inheritance uncovered in new study
Researchers at RIKEN have uncovered a mechanism by which the effects of stress in the fly species Drosophila are inherited epigenetically over many generations through changes to the structure of chromatin, ...
Jun 23, 2011 |
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Stress protein Hsp12 provides a cellular survival mechanism never seen before
Despite clear evidence that Hsp12 -- a so-called heat shock or stress protein -- helps cells survive life-threatening conditions, how it works was an open question until now. The surprising answer is revealed ...
Aug 26, 2010 |
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Inhibitor of Heat Shock Protein is a Potential Anticancer Drug, Study Finds
(PhysOrg.com) -- Like yoga for office drones, cells do have coping strategies for stress. Heat, lack of nutrients, oxygen radicals - all can wreak havoc on the delicate internal components of a cell, potentially ...
Oct 29, 2009 |
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Structure of protective protein in the eye lens revealed
The human eye lens consists of a highly concentrated mix of several proteins. Protective proteins prevent these proteins from aggregating and clumping. If this protective function fails, the lens blurs and ...
Jul 31, 2009 |
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Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease
Dissecting how heat shock protein 90 gets steroid receptors into shape to use hormones like estrogen and testosterone could lead to targeted therapies for hormone-driven cancers, such as breast and prostate, ...
Jun 22, 2009 |
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New biosensor for most serious form of Listeria food poisoning bacteria
(PhysOrg.com) -- Scientists in Indiana are reporting development of a new biosensor for use in a faster, more sensitive test for detecting the deadliest strain of Listeria food poisoning bacteria. That microbe ...
Chemistry / Analytical Chemistry
Apr 23, 2009 |
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Recent advance in detonation theory
A detonation wave is a chemical reaction wave propagating at the velocity of a shock wave along the explosive charge. There is great demand for a detonation model that can accurately simulate the detonation process, which ...
Nov 18, 2011 |
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