Receptor location in heart plays a key role in their function

In the heart there are two different subtypes of beta-adrenergic receptors—beta1 and beta2—which are activated by the stress hormones adrenaline and noradrenaline. They both trigger the strongest stimulation of the heart ...

Researchers transform common cell to master heart cell

By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin-Madison have generated master heart cells—primitive progenitors that form the developing ...

Growth factor essential to epicardial cell function: research

In research that one day may lead to the discovery of how to regenerate tissue damaged by heart disease, investigators at Childrens Hospital Los Angeles have identified PDGF as a key factor in the proliferation and transformation ...

How the zebrafish repairs a broken heart

An MDC research team led by Jan Philipp Junker and Daniela Panáková has found that zebrafish can regenerate heart tissue after injury. Connective tissue cells play an important role in the process by temporarily entering ...

Two mutations are better than one

Two wrongs don't make a right, but in the case of genetic mutations, having two mutations in the same gene could be better than having either one individually. Recent research by biologists at San Diego State University found ...

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