News tagged with growth signals

Study strengthens link between sirtuins proteins and life extension

(PhysOrg.com) -- A new paper from MIT biology professor Leonard Guarente strengthens the link between longevity proteins called sirtuins and the lifespan-extending effects of calorie restriction.

Medicine & Health / Medical research

created Dec 14, 2009 | popularity 4.8 / 5 (10) | comments 1

Researchers seek to put the squeeze on cancer

(PhysOrg.com) -- Cancer researchers have been studying angiogenesis — the growth of new blood vessels — since the early 1970s, when Judah Folkman first theorized that tumors could be destroyed by cutting off ...

Medicine & Health / Cancer

created Jun 15, 2010 | popularity 5 / 5 (8) | comments 0 | with audio podcast

Scientists pinpoint link between light signal and circadian rhythms

In a new paper published this week in the Proceedings of the National Academy of Sciences, Aziz Sancar, MD, PhD, the Sarah Graham Kenan Professor of Biochemistry and Biophysics in the UNC School of Medicine, and his collea ...

Biology / Cell & Microbiology

created Dec 29, 2010 | popularity 4.5 / 5 (8) | comments 0 | with audio podcast

Yale scientists find stem cells that tell hair it's time to grow

Yale researchers have discovered the source of signals that trigger hair growth, an insight that may lead to new treatments for baldness.

Biology / Cell & Microbiology

created Sep 01, 2011 | popularity 5 / 5 (7) | comments 8 | with audio podcast

Drug discovery short-circuits cancer growth

A new drug that blocks cancer's main source of growth has been created in the lab and proven effective in mice, scientists are reporting. It is now being readied for clinical trials in patients.

Biology /

created Feb 10, 2009 | popularity 4.7 / 5 (7) | comments 1

Cellular mechanical forces may initiate angiogenesis

Pericytes, the contractile cells surrounding capillaries, may use mechanical forces to initiate angiogenesis, the "sprouting" of new blood vessels, according to researchers at Tufts University School of Medicine (TUSM) and ...

Physics / Condensed Matter

created Apr 26, 2010 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Discovery of key pathway interaction may lead to therapies that aid brain growth and repair

Researchers at Children's National Medical Center have discovered that the two major types of signaling pathways activated during brain cell development -- the epidermal growth factor receptor pathway and the Notch pathway ...

Medicine & Health / Neuroscience

created Sep 16, 2010 | popularity 5 / 5 (4) | comments 0

Researchers identify potential target for metastatic cancer

The deadliest part of the cancer process, metastasis, appears to rely on help from macrophages, potent immune system cells that usually defend vigorously against disease, researchers at Albert Einstein College ...

Medicine & Health / Cancer

created Aug 10, 2009 | popularity 5 / 5 (3) | comments 0

Scientists present first model of how buds grow into leaves

Leaves come in all shapes and sizes. Scientists have discovered simple rules that control leaf shape during growth. Using this 'recipe', they have developed the first computer model able to accurately emulate ...

Biology / Plants & Animals

created Mar 01, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Research involving thyroid hormone lays foundation for more targeted drug development

Research led by St. Jude Children's Research Hospital scientists advances a strategy for taming the side effects and enhancing the therapeutic benefits of steroids and other medications that work by disrupting the activity ...

Chemistry / Biochemistry

created Oct 21, 2011 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Chemists reveal the force within you

A new method for visualizing mechanical forces on the surface of a cell, reported in Nature Methods, provides the first detailed view of those forces, as they occur in real-time.

Chemistry / Biochemistry

created Nov 09, 2011 | popularity 4 / 5 (2) | comments 4 | with audio podcast

Wistar researchers show targeting 'normal' cells in tumors slows growth

Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.

Medicine & Health / Cancer

created Nov 16, 2009 | popularity 3 / 5 (2) | comments 0

Capillary formation’s mechanical determinants: One growth factor can have many effects

(PhysOrg.com) -- Harvard researchers have established a link between the growth of blood vessels and the mechanical stresses caused by the environment within which the vessels grow, a new understanding that ...

Medicine & Health / Medical research

created Mar 09, 2009 | popularity 5 / 5 (1) | comments 0

Scientists show how brain tumors outsmart drugs

Researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine and Moores UCSD Cancer Center have shown one way in which gliomas, a deadly type of brain tumor, ...

Medicine & Health / Cancer

created Jan 19, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Zebrafish swim into drug development

By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.

Chemistry / Biochemistry

created Jan 21, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast