News tagged with growth pathway
Researchers use light to measure cancer cells' response to treatment
Many cancer therapies target specific proteins that proliferate on the outside of some cancer cells, but the therapies are imperfect and the cancer does not always respond. Since it is beneficial for doctors to know as soon ...
Dec 20, 2011 |
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Protein love triangle key to crowning bees queens?
A honey bee becomes a royal queen or a common worker as a result of the food she receives as a larva. While it has been well established that royal jelly is the diet that makes bees queens, the molecular path ...
Nov 10, 2011 |
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Chemists reveal the force within you
A new method for visualizing mechanical forces on the surface of a cell, reported in Nature Methods, provides the first detailed view of those forces, as they occur in real-time.
Nov 09, 2011 |
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Biologists learn how plants synthesize their growth hormone auxin
Biologists at the University of California, San Diego have succeeded in unraveling, for the first time, the complete chain of biochemical reactions that controls the synthesis of auxin, the hormone that regulates nearly all ...
Oct 24, 2011 |
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Research involving thyroid hormone lays foundation for more targeted drug development
Research led by St. Jude Children's Research Hospital scientists advances a strategy for taming the side effects and enhancing the therapeutic benefits of steroids and other medications that work by disrupting the activity ...
Oct 21, 2011 |
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A new role for cytokinin plant hormones
When plants, including crops, are exposed to environmental stresses such as drought or high salinity, abscisic acid (ABA), a stress-responsive hormone is synthesized to induce a protective response. At the same time, the ...
Sep 09, 2011 |
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Researchers uncover hormone pathway to fatty liver disease
Scientists at the UCSF Cardiovascular Research Institute have discovered how a change in growth hormone activity in mice leads to fatty liver disease, a condition whose human counterpart is of rising concern worldwide.
Medicine & Health / Medical research
Mar 01, 2011 |
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Apoptotic mechanisms of octreotide on HepG2
A research team from Greece examined the effect of octreotide on cellular proliferation, apoptosis and caspase activation in HepG2 hepatocellular carcinoma (HCC) cells. The results supported the induction of caspase-mediated ...
Jan 31, 2011 |
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Study raises safety concerns about experimental cancer approach
A study by researchers at Washington University School of Medicine in St. Louis has raised safety concerns about an investigational approach to treating cancer.
Jan 25, 2011 |
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Pazopanib shows promise in Phase II trial for relapsed/refractory urothelial cancer
An ongoing Phase-II trial investigating a new, targeted therapy for metastatic urothelial cancer has generated promising early results, Italian researchers reported at the 35th Congress of the European Society for Medical ...
Oct 12, 2010 |
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A 'giant' step toward explaining differences in height: Scientists map height 'hotspots' in the genome
(PhysOrg.com) -- An international collaboration of more than 200 institutions, led by researchers at Children's Hospital Boston, the Broad Institute, and a half-dozen other institutions in Europe and North ...
Sep 29, 2010 |
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Discovery of key pathway interaction may lead to therapies that aid brain growth and repair
Researchers at Children's National Medical Center have discovered that the two major types of signaling pathways activated during brain cell development -- the epidermal growth factor receptor pathway and the Notch pathway ...
Medicine & Health / Neuroscience
Sep 16, 2010 |
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Selective inhibition of BMK1 suppresses tumor growth
A study describing a newly developed pharmacological inhibitor is providing detailed insight into how an enzyme that has been implicated in multiple human malignancies regulates a known tumor suppressor. The research, published ...
Sep 13, 2010 |
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Estrogen receptor status of HER2+ breast cancer correlates with response to anti-HER therapies
An international team of researchers has discovered molecular evidence that may explain why some women with HER2 over-expressing breast cancer do not respond to drugs designed to target this important molecule.
May 06, 2010 |
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Zebrafish swim into drug development
By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.
Jan 21, 2010 |
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