News tagged with glycoproteins
Efficient preparation of a set of potential glycosidase inhibitors
(Phys.org) -- In many biological and pathological processes, glycosidase enzymes attack glycosidic bonds in carbohydrates, glycoproteins, and glycolipids. The ability to modify or block these processes by ...
May 29, 2012 |
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Scientists find new way to attack cancerous cells
Scripps Research Institute scientists have discovered a new way to target and destroy a type of cancerous cell. The findings may lead to the development of new therapies to treat lymphomas, leukemias, and related cancers.
Jun 07, 2010 |
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Parasite breaks its own DNA to avoid detection
The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise. Every time the host's immune cells get close to destroying the parasite, it escapes detection by rearranging its DN ...
Apr 15, 2009 |
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Spider web glue spins society toward new biobased adhesives
With would-be goblins and ghosts set to drape those huge fake spider webs over doorways and trees for Halloween, scientists in Wyoming are reporting on a long-standing mystery about real spider webs: It is ...
Oct 21, 2009 |
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Pacific Ocean natural products isolated from marine mollusks, sponges can reverse multidrug resistance in cancer cells
(Phys.org) -- Many marine natural products show anticancer activity, but some can reverse multidrug resistance in cancer cells. A new investigation by Robert J. Capon of the University of Queensland correlates ...
Apr 12, 2012 |
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'Lubricin' molecule discovered to reduce cartilage wear
A team of researchers in North Carolina has discovered that lubricin, a synovial fluid glycoprotein, reduces wear to bone cartilage. This result, which has implications for the treatment of sufferers of osteoarthritis, will ...
Medicine & Health / Medical research
Oct 21, 2010 |
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Elucidation of the 3D structure of Chikungunya virus
French researchers at the Pasteur Institute and the CNRS, in collaboration with the Synchrotron SOLEIL, have solved the three-dimensional structures of the glycoproteins that envelop the chikungunya virus. ...
Medicine & Health / Medical research
Dec 06, 2010 |
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Antibodies Against Abnormal Glycoproteins Identified as Possible Biomarkers for Cancer Detection
(PhysOrg.com) -- Scientists have found that cancer patients produce antibodies that target abnormal glycoproteins (proteins with sugar molecules attached) made by their tumors. The result of this work suggests that antitumor ...
Feb 02, 2010 |
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New mechanism explains how the body prevents formation of blood vessels
Researchers at Uppsala University, in collaboration with colleagues in Sweden and abroad, have identified an entirely new mechanism by which a specific protein in the body inhibits formation of new blood vessels. Inhibiting ...
Nov 11, 2009 |
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Study answers question of timing in use of eptifibatide
An international study to resolve a decade of debate over the best timing for administering an anti-clotting drug for certain heart patients has come up with an answer: It doesn't matter.
Medicine & Health / Medical research
Mar 30, 2009 |
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Scientists clear the way to alternative anti-angiogenic cancer therapy
Belgian scientists attached to VIB and K.U.Leuven have succeeded in decoding a potential new anti-cancer mechanism. The researchers discovered that normalizing abnormal tumor blood vessels through HRG (histidine-rich glycoprotein) ...
Jan 07, 2011 |
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Enzyme with a Sugar Antenna: Researchers achieve semisynthesis of homogeneous glycoproteins
(PhysOrg.com) -- More than half of all human proteins, as well as many important pharmaceutical agents, are glycoproteins, which means that they contain sugar components. In general, natural glycoproteins ...
Jan 30, 2009 |
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Drug-eluting stents better than bare-metal stents for heart attack patients
Late-breaking data from the landmark HORIZONS-AMI clinical trial, presented at the 21st annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, demonstrated that after two years, in heart attack patients, ...
Sep 25, 2009 |
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Biomarkers detected for Chikungunya fever
Three specific biomarkers provide an accurate indication of the severity of Chikungunya fever (CHIKF), which is emerging as a threat in South-East Asia, the Pacific and Europe, according to research conducted in Singapore.
Mar 04, 2009 |
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Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. In proteins that have segments extending extracellularly, the extracellular segments are often glycosylated. Glycoproteins are often important integral membrane proteins, where they play a role in cell–cell interactions. Glycoproteins also occur in the cytosol, but their functions and the pathways producing these modifications in this compartment are less well-understood.
For more information about Glycoprotein, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
