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Highly efficient CRISPR knock-in in mouse

Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...

dateMay 01, 2015 in Biotechnology
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Longer DNA fragments reveal rare species diversity

A challenge in metagenomics is that the more commonly used sequencing machines generate data in short lengths, while short-read assemblers may not be able to distinguish among multiple occurrences of the same or similar sequences, ...

dateApr 01, 2015 in Biotechnology
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UNESCO experts call for ban on genetic 'editing'

A UNESCO panel of scientists, philosophers, lawyers and government ministers called Monday for a halt to genetic "editing" of the human germline, warning of the danger of tampering with hereditary traits that could lead to ...

dateOct 05, 2015 in Biotechnology
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Raw material for new genes

Every region of DNA codes for a gene. Well, not quite. Although an organism's genome contains some regions that are read and transcribed into RNA, many of those do not give rise to functional genes. Scientists at the Max ...

dateMar 08, 2016 in Biotechnology
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