News tagged with genetic splicing
Research uncovers new exception to decades-old rule about RNA splicing
There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
May 17, 2012 |
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The splice of life: Proteins cooperate to regulate gene splicing
Understanding how RNA binding proteins control the genetic splicing code is fundamental to human biology and disease – much like editing film can change a movie scene. Abnormal variations in splicing ...
Feb 16, 2012 |
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Temperature controls the genetic message
Alternative splicing, the mechanism enabling a gen to encode different proteins, according to the cell's needs, still holds many secrets. It has transformed the initial theory of one gen, one protein, but how it is controlled ...
Sep 16, 2011 |
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Researchers discover a switch that controls stem cell pluripotency
Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency is regulated by a single ...
Sep 15, 2011 |
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Genetic mutation linked to lethal disease
Researchers have identified a genetic mutation found in the Ohio Amish population as the cause of a fatal developmental disease in fetuses and infants, according to research published in the April 8, 2011, issue of Science.
Apr 18, 2011 |
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Engineered molecule changes itself to detect and attack diseased cells
(PhysOrg.com) -- Assistant Professor of Bioengineering Christina Smolke has engineered biological molecules that regulate a cell's behavior by adjusting their own forms and functions in response to the internal conditions ...
Nov 30, 2010 |
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Researchers crack 'splicing code,' solve a mystery underlying biological complexity
Researchers at the University of Toronto have discovered a fundamentally new view of how living cells use a limited number of genes to generate enormously complex organs such as the brain.
May 05, 2010 |
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Spying on a cellular director in the cutting room
Like a film director cutting out extraneous footage to create a blockbuster, the cellular machine called the spliceosome snips out unwanted stretches of genetic material and joins the remaining pieces to fashion a template ...
Mar 21, 2010 |
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Possible help in fight against muscle-wasting disease (w/ Video)
(PhysOrg.com) -- A compound already used to treat pneumonia could become a new therapy for an inherited muscular wasting disease, according to researchers at the University of Oregon and the University of ...
Medicine & Health / Medical research
Nov 06, 2009 |
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Of yeast and men: Unraveling the molecular mechanisms of Friedreich's ataxia
Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Jul 09, 2009 |
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