(Phys.org) —These days, getting a Ph.D. is probably the last thing you want to do if you are out to revolutionize the world. If, however, what you propose is an idea, rather than a technology, it can still be a valuable ...
Earth could contain nearly 1 trillion species, with only one-thousandth of 1 percent now identified, according to the results of a new study.
Ecology
May 20, 2016
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244
Researchers at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (VMBS) and an interdisciplinary team of collaborators have uncovered new information about the history of cat evolution explaining how cats—including ...
Plants & Animals
Nov 2, 2023
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1464
In the early 1960s, University of Michigan alumnus Marshall Nirenberg and a few other scientists deciphered the genetic code of life, determining the rules by which information in DNA molecules is translated into proteins, ...
Evolution
Jun 8, 2022
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421
The Y chromosome may be a symbol of masculinity, but it is becoming increasingly clear that it is anything but strong and enduring. Although it carries the "master switch" gene, SRY, that determines whether an embryo will ...
Evolution
Jul 13, 2020
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627
(PhysOrg.com) -- Studying chemical modifications in the chromosomes of cells is akin to searching for changes in coiled spaghetti. Scientists at Cornell have figured out how to stretch out tangled strands of DNA from chromosomes, ...
Analytical Chemistry
Oct 31, 2011
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0
The extinction of prehistoric megafauna like the woolly mammoth, cave lion, and woolly rhinoceros at the end of the last ice age has often been attributed to the spread of early humans across the globe. Although overhunting ...
Archaeology
Aug 13, 2020
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1842
For most of our evolutionary history—for most of the time anatomically modern humans have been on Earth—we've shared the planet with other species of humans. It's only been in the last 30,000 years, the mere blink of ...
Archaeology
Dec 19, 2019
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3116
Scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh have discovered an enzyme that corrects the most common mistake in mammalian DNA.
Cell & Microbiology
May 10, 2012
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0
Yekaterina "Kate" Shulgina was a first year student in the Graduate School of Arts and Sciences, looking for a short computational biology project so she could check the requirement off her program in systems biology. She ...
Biotechnology
Nov 9, 2021
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187
A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.
The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."
Sequences can be derived from the biological raw material through a process called DNA sequencing.
In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:
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