DNA gridlock: Cells undo glitches to prevent mutations
Roughly six feet of DNA are packed into every human cell, so it is not surprising that our genetic material occasionally folds into odd shapes such as hairpins, crosses and clover leafs. But these structures ...
Team finds key to gene-silencing activity, opens door to new class of therapies
A team led by scientists at The Scripps Research Institute (TSRI) has found how to boost or inhibit a gene-silencing mechanism that normally serves as a major controller of cells' activities. The discovery ...
Pig stress syndrome linked to gene defect
How herpesvirus invades nervous system: Viral protein hijacks cellular machinery and grabs the wheel
Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.
Out of Africa date brought forward
(Phys.org) —A study on human mitochondrial DNA has led to a new estimate of the time at which humans first began to migrate out of Africa, which was much later than previously thought.
Skulls of early humans carry telltale signs of inbreeding, study says
Buried for 100,000 years at Xujiayao in the Nihewan Basin of northern China, the recovered skull pieces of an early human exhibit a now-rare congenital deformation that indicates inbreeding might well have ...
Researchers show gene controlling coat color in mice mutated nine times, results shed new light on how evolution works
Hereditary neurodegeneration linked to ADP-ribose modification
Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
Scientists focus on another Sandy loss—lab mice
How did early primordial cells evolve?
Four billion years ago, soon after the planet cooled enough for life to begin, primordial cells may have replicated and divided without protein machinery or cell walls, relying instead on just a flimsy lipid membrane. New ...
Evolution and the ice age: Tracing the effects of climate change on prehistoric and future environments
Genetic variation controls predation: Benefits of being a mosaic
A genetically mosaic Eucalyptus tree is able to control which leaves are saved from predation because of alterations in its genes, finds an study published in BioMed Central's open access journal BMC Plant Bi ...
How predictable is evolution?
Novel diagnostic method supports skin cancer therapy
(Phys.org)—Malignant melanoma is the most aggressive type of skin cancer. In more than 50 percent of affected patients a particular mutation plays an important role. As the life span of the patients carrying ...