There is great potential in gene therapy for treating certain types of cancer and genetic defects, immunological diseases, wounds and infections. The therapies work by delivering genes into the patients' cells, which then ...
Bio & Medicine
Oct 7, 2020
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Geneticist Jolanda van Leeuwen remembers the day she made a striking observation that would take her down a new research path. A strain of yeast cells carrying a complete deletion of an essential gene in their genomes, which ...
Cell & Microbiology
Sep 30, 2020
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Zebrafish are one of the most well studied animals on the planet. But how they came by their beautiful black and gold stripes is more of a mystery. Our new research used mathematical modeling—and detailed observations of ...
Plants & Animals
Jul 28, 2020
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Warmblood fragile foal syndrome is a severe, usually fatal, genetic disease that manifests itself after birth in affected horses. Due to the defect, the connective tissue is unstable. Under force, for instance, the skin tears ...
Veterinary medicine
Jul 15, 2020
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Three teams working independently to test the possibility of using CRISPR–Cas9 gene editing to remove genetic defects in human embryos report finding unwanted changes in the genomes. The first team, working at the Francis ...
Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...
Cell & Microbiology
May 5, 2020
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29
At first glance, there aren't many similarities between westslope cutthroat trout in Montana, wolves on Isle Royale National Park in Michigan and Australia's mountain pygmy possum, a mouse-sized alpine marsupial.
Evolution
Jul 17, 2019
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Genetic diseases are fairly common today, with more than one in 25 children being born with one. But the evolutionary history of such conditions is mysterious. Which genetic disorders were common in our ancestors and why? ...
Archaeology
Apr 1, 2019
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Experts from seven countries called Wednesday for a moratorium on the kind of genetic manipulation—known as germline editing—used last year to permanently modify the genome of twin girls in Shenzhen, China.
Biotechnology
Mar 14, 2019
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10
After decades of work with no success, researchers have determined the high-resolution, three-dimensional structure for lipoprotein lipase, the enzyme that processes fats, or triglycerides, in the bloodstream and releases ...
Biochemistry
Feb 26, 2019
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