Invasive weeds could shed light on climate-coping
Hereditary neurodegeneration linked to ADP-ribose modification
Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
Mar 12, 2013
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Cell biology: Flushing out fats
The Wip1 protein is important for survival, but mutations that inactivate it carry some surprising features. "A lack of Wip1 results in an excessive immune reaction to infectious organisms, in some cases ...
Dec 19, 2012
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Microbial 'missing link' discovered after man impales hand on tree branch
(Phys.org)—It all started with a crab apple tree. Two years ago, a 71-year-old Indiana man impaled his hand on a branch after cutting down a dead tree. The wound caused an infection that led scientists ...
Nov 26, 2012
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How insects domesticate bacteria: Symbiotic microbes' origin discovered after man impales hand on branch
Two years ago, a 71-year-old Indiana man impaled his hand on a branch after cutting down a dead crab apple tree, causing an infection that led University of Utah scientists to discover a new bacterium and ...
Nov 15, 2012
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New laboratory test assesses how DNA damage affects protein synthesis
Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Aug 21, 2012
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When inflexibility is counterproductive: Mechanism of UV-induced DNA Dewar lesion revealed
Excessive exposure to ultraviolet (UV) radiation of sunlight can result in skin damage and may even induce skin cancers. Irradiation with UV light causes mutations in the DNA, which can interfere with or even inhibit the ...
Nov 28, 2011
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Study identifies a key molecular switch for telomere extension by telomerase
Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ...
Nov 23, 2011
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Do bacteria age? Biologists discover the answer follows simple economics
When a bacterial cell divides into two daughter cells and those two cells divide into four more daughters, then 8, then 16 and so on, the result, biologists have long assumed, is an eternally youthful population of bacteria. ...
Oct 27, 2011
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Biochemists identify new genetic code repair tool
Clemson University researchers recently reported finding a new class of DNA repair-makers.
Sep 27, 2011
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Cellular metabolism self-adapts to protect against free radicals
Oxygen-consuming organisms obtain energy through cellular respiration, which is the transformation of carbohydrates and oxygen into carbon dioxide and water. This process also produces toxic oxygen radicals which must be ...
Sep 07, 2011
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A chaperone for the 'guardian of the genome'
The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...
Sep 07, 2011
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Genetic evidence clears Ben Franklin (w/ Video)
Researchers find link between DNA damage and immune response
Researchers offer the first evidence that DNA damage can lead to the regulation of inflammatory responses, the body's reaction to injury. The proteins involved in the regulation help protect the body from infection.
Mar 31, 2011
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Gene is linked to colon cancer when folate's low
(PhysOrg.com) -- Cornell researchers report that they have identified a gene that increases the risk for colon cancer in laboratory mice when their diets lack folate.
Mar 29, 2011
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