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Toward an expression atlas for an entire brain

Researchers who study how genes are expressed across a given tissue can now examine thousands of genes at once at cellular resolution, thanks to new methods developed at EMBL and published in Nature Biotechnology. The ne ...

dateApr 14, 2015 in Biotechnology
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How an RNA gene silences a whole chromosome

Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, ...

dateApr 27, 2015 in Biotechnology
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Highly efficient CRISPR knock-in in mouse

Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without ...

dateMay 01, 2015 in Biotechnology
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