A not-so-selfish 'genetic parasite' helps to preserve fertility

Ribosomal DNA (rDNA) sequences are essential parts of many species' genomes. The highly repetitive nature of these DNA sequences makes them susceptible to shrinkage over timeā€”and if they shrink too much, cells die. If rDNA ...

Uncovering hidden mitochondrial mutations in single cells

A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for assessing mtDNA editing strategies ...

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