Which came first the head or the brain?
New key to organism complexity identified: Critical transcription factor co-exists in two distinct states
Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate ...
Jan 17, 2013
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New study challenges old views about evolution of early life
A research team led by biogeochemists at the University of California, Riverside has tested a popular hypothesis in paleo-ocean chemistry, and proved it false.
Dec 23, 2012
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Scientists observe single gene activity in living cells
Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...
Apr 21, 2011
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Scientists ferret out a key pathway for aging
For decades, scientists have been searching for the fundamental biological secrets of how eating less extends lifespan.
Nov 18, 2010
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Our genes can be set on pause
New evidence in embryonic stem cells shows that mammalian genes may all have a layer of control that acts essentially like the pause button on your DVR. The researchers say the results show that the pausing phenomenon, previously ...
Apr 29, 2010
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Mapping a route to stem cell therapies
Monash University researchers are shedding light on the complex processes that underpin the creation and differentiation of stem cells, bringing closer the promise of 'miracle' therapies.
May 20, 2013
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Study shows reproductive effects of pesticide exposure span generations
Healing by the clock: In fruit flies, intestinal stem-cell regeneration fluctuates with the time of day
Circadian rhythms keep time for all living things, from regulating when plants open their flowers to foiling people when they try to beat jet lag. Day-night cycles are controlled through ancient biological ...
Apr 11, 2013
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Epigenetic control of cardiogenesis: Non-coding RNA is essential for normal embryonic cardiogenesis
Many different tissues and organs form from pluripotent stem cells during embryonic development. To date it had been known that these processes are controlled by transcription factors for specific tissues. ...
Jan 29, 2013
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Evolution: Alternative splicing of RNA rewires signaling in different tissues, may contribute to species differences
Biologists unlocking the secrets of plant defenses, one piece at a time
Researchers examining how the hormone jasmonate works to protect plants and promote their growth have revealed how a transcriptional repressor of the jasmonate signaling pathway makes its way into the nucleus of the plant ...
Dec 05, 2012
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Systems biology meets epigenetics: A computational model explains epigenome dynamics during differentiation
(Phys.org)—Scientists from the Friedrich Miescher Institute for Biomedical Research and the Biozentrum of the University of Basel have published an important proof-of-principle study showing that a computational ...
Dec 04, 2012
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Humans, chimpanzees and monkeys share DNA but not gene regulatory mechanisms
Humans share over 90% of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.
Nov 06, 2012
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Watching the cogwheels of the biological clock in living cells
Our master circadian clock resides in a small group of about 10'000 neurons in the brain, called the suprachiasmatic nucleus. However, similar clocks are ticking in nearly all cells of the body, as demonstrated ...
Oct 26, 2012
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