News tagged with gene transcription

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Regulating hematopoietic differentiation

Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...

dateOct 05, 2012 in Cell & Microbiology
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Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. ...

dateSep 25, 2012 in Cell & Microbiology
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The controlled cell

(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported ...

dateSep 07, 2012 in Cell & Microbiology
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Transcription runs like clockwork

(Phys.org)—It's not just a few key genes and proteins that cycle on and off in humans in a 24-hour circadian pattern as the sun rises and falls. Thousands of genes in organs throughout the body show predictable daily fluctuations, ...

dateSep 03, 2012 in Cell & Microbiology
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Biophysicists unravel secrets of genetic switch

When an invading bacterium or virus starts rummaging through the contents of a cell nucleus, using proteins like tiny hands to rearrange the host's DNA strands, it can alter the host's biological course. The invading proteins ...

dateAug 30, 2012 in General Physics
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