News tagged with gene transcription

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Regulating hematopoietic differentiation

Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms ...

Oct 05, 2012
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Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, ...

Sep 25, 2012
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The controlled cell

(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the ...

Sep 07, 2012
not rated yet 0 | with audio podcast

Transcription runs like clockwork

(Phys.org)—It's not just a few key genes and proteins that cycle on and off in humans in a 24-hour circadian pattern as the sun rises and falls. Thousands of genes in organs throughout the body show predictable daily fluctuations, ...

Sep 03, 2012
5 / 5 (2) 0 | with audio podcast

Biophysicists unravel secrets of genetic switch

When an invading bacterium or virus starts rummaging through the contents of a cell nucleus, using proteins like tiny hands to rearrange the host's DNA strands, it can alter the host's biological course. The invading proteins ...

Aug 30, 2012
5 / 5 (5) 0 | with audio podcast