For the past 20 years, researchers have been trying to perfect the construction of human artificial chromosomes, or HACs for short. In a paper published today in Cell, Penn researchers describe a new way to form an essential ...
Molecular & Computational biology
Jul 25, 2019
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52
The applications of CRISPR based genetic engineering tools range from changing colors in butterfly wings to developing gene therapies that might one day cure or prevent human diseases.
Biotechnology
Jun 26, 2019
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1
A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...
Biochemistry
Jun 13, 2019
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4
A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for ...
Biotechnology
Jun 12, 2019
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535
Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells. Using a gold nanoparticle instead of an inactivated ...
Materials Science
May 27, 2019
3
193
IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
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83
Viruses are often used as vehicles for delivery in gene therapy because they're engineered not to damage the cell once they get there, but neglecting to consider how the virus will exit the cell could have consequences.
Cell & Microbiology
Apr 5, 2019
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142
Recent studies have suggested a potential barrier to making CRISPR gene-editing treatments a viable option for inherited blood-related disorders such as sickle cell anemia, thalassemia, and primary immunodeficiency syndromes. ...
Biotechnology
Mar 21, 2019
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100
Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.
Biotechnology
Mar 6, 2019
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581
Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. This new invention can greatly contribute to more effective and selective ...
Bio & Medicine
Feb 8, 2019
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369
