For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected. Delivery of the vector ...
Biotechnology
Feb 1, 2016
1
13
A summit of experts from around the world is meeting in Washington to consider the scientific, ethical and governance issues linked to research into gene editing. Convened in response to recent advances in the field, the ...
Biotechnology
Dec 2, 2015
0
31
The source of any life involves the duplication (or replication) of DNA, a mechanism that is essential to cell division. A team of biologists has recently performed the most exhaustive analysis to date of thousands of sites ...
Biotechnology
Nov 12, 2015
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22
We depend on electrical waves to regulate the rhythm of our heartbeat. When those signals go awry, the result is a potentially fatal arrhythmia. Now, a team of researchers from Oxford and Stony Brook universities has found ...
Optics & Photonics
Oct 19, 2015
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2319
New research published today in the journal eLife has demonstrated a new method for observing the behaviour of the protein Dystrophin in a living animal cell, in real-time. This breakthrough may provide a key to understanding ...
Cell & Microbiology
Oct 13, 2015
0
10
People with congenital stationary night blindness, or CSNB, have normal vision during the day but find it difficult or impossible to distinguish objects in low light. This rare condition is present from birth and can seriously ...
Plants & Animals
Sep 14, 2015
0
17
Researchers have recreated the evolutionary lineage of adeno-associated viruses (AAVs) to reconstruct an ancient viral particle that is highly effective at delivering gene therapies targeting the liver, muscle, and retina. ...
Cell & Microbiology
Jul 30, 2015
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107
CRISPR/Cas systems for genome editing have revolutionized biological research over the past three years, and their ability to make targeted changes in DNA sequences in living cells with relative ease and affordability is ...
Cell & Microbiology
Jul 20, 2015
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20
To overcome the off-target mutations that commonly occur with CRISPR/Cas9 genome editing methods, researchers at Harvard Medical School and Massachusetts General Hospital have developed two strategies that greatly improve ...
Biotechnology
Jul 20, 2015
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45
Adenoviruses cause numerous diseases, such as eye or respiratory infections, and they are widely used in gene therapy. Researchers from the University of Zurich have now discovered how these viruses penetrate the cells, a ...
Cell & Microbiology
Jul 9, 2015
0
14
