News tagged with gene therapeutics
Researchers solve structure of human protein critical for silencing genes
In a study published in the journal Cell on May 24, Cold Spring Harbor Laboratory (CSHL) scientists describe the three-dimensional atomic structure of a human protein bound to a piece of RNA that "guides" the pr ...
May 25, 2012 |
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First description of a triple DNA helix in a vacuum
A team of researchers at the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC) have managed for the first time to extract trustworthy structural information ...
Apr 18, 2012 |
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An 'immortal' devil's genome and the secrets of a cancer that's catching
Researchers reporting in the February 17th issue of the Cell Press journal Cell have sequenced the complete genome of one immortal devil. The genomes of the Tasmanian devil and its transmissible cancer may he ...
Feb 16, 2012 |
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Researchers develop CAD-Type tools for engineering RNA control systems
The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the Joint BioEnergy ...
Dec 22, 2011 |
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Nanochannel electroporation: Researchers do precise gene therapy without a needle
For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle.
Nanotechnology / Bio & Medicine
Oct 16, 2011 |
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Researchers publish paper on CHO-K1 cell genome sequencing
The Chinese Hamster Ovary (CHO) cell is one of the most preferred hosts used to manufacture therapeutic proteins -- genes that are added to "cell factories" to produce proteins that are later turned into medicines.
Aug 05, 2011 |
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Genome editing, a next step in genetic therapy, corrects hemophilia in animals
Using an innovative gene therapy technique called genome editing that hones in on the precise location of mutated DNA, scientists have treated the blood clotting disorder hemophilia in mice. This is the first time that genome ...
Jun 26, 2011 |
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A novel prognostic marker for biliary atresia
A research team from China characterized the differentially expressed gene profiles in livers from biliary atresia (BA) patients. They found that RRAS gene and its related MAPK pathway are important regulatory modules in ...
Mar 08, 2011 |
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New technology provides first view of DNA damage within entire human genome
New technology providing the first view of DNA damage throughout the entire human genome developed by Cardiff University scientists could offer a valuable new insight into the development and treatment of conditions like ...
Jan 18, 2011 |
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In Parkinson's disease, brain cells abandon mitochondria
In a study that sheds new light on the causes of Parkinson's disease, researchers report that brain cells in Parkinson's patients abandon their energy-producing machinery, the mitochondria. A shutdown in fuel can have devastating ...
Medicine & Health / Medical research
Oct 06, 2010 |
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Paper highlight: Signaling hope for polycystic kidney disease
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a common genetic disease that results in chronic kidney failure.
Medicine & Health / Diseases, Conditions, Syndromes
Sep 13, 2010 |
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Rare variants in gene coding may up risk of autoimmune disorders
(PhysOrg.com) -- Rare variants in the gene coding of an enzyme that controls the activity of a key immune cell occur more often in people with autoimmune disorders like rheumatoid arthritis and type 1 diabetes, ...
Jul 01, 2010 |
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Treatment resistance in some cancer cells may be reversible
(PhysOrg.com) -- The ability of cancer cells to resist treatment with either targeted drug therapies or traditional chemotherapy may, in some cases, result from a transient state of reversible drug "tolerance." ...
Apr 01, 2010 |
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Second dose of gene therapy for inherited blindness proves safe in animal studies
Gene therapy for a severe inherited blindness, which produced dramatic improvements last year in 12 children and young adults who received the treatment in a clinical trial, has cleared another hurdle. The ...
Mar 03, 2010 |
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Researchers publish review of the 'molecular basis of colorectal cancer'
Every year in the United States, 160,000 cases of colorectal cancer are diagnosed, and 57,000 patients die of the disease, making it the second leading cause of death from cancer among adults, after lung cancer.
Dec 16, 2009 |
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