News tagged with gene splicing
Research uncovers new exception to decades-old rule about RNA splicing
There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process. The rule-flaunting ...
May 17, 2012 |
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Cancer-associated long non-coding RNA regulates pre-mRNA splicing
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Sep 23, 2010 |
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Of yeast and men: Unraveling the molecular mechanisms of Friedreich's ataxia
Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Jul 09, 2009 |
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Getting more from whole-transcript microarrays
The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...
May 21, 2009 |
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Siestas Among the Drosophilae
(PhysOrg.com) -- Isaac Edery is concerned with biological clocks, internal mechanisms that enable virtually all plants and animals to behave in rhythmic biological cycles known as circadian rhythms.
Biology /
Jan 28, 2009 |
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Scientists clarify editing error underlying genetic neurodegenerative disease
Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia ...
Biology /
Jan 28, 2009 |
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