Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate the process by which ...
Cell & Microbiology
Jan 17, 2013
0
0
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Biotechnology
Aug 18, 2011
0
0
Researchers from Carnegie Mellon University's School of Computer Science have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing ...
Cell & Microbiology
Apr 9, 2024
0
140
G-quadruplexes (G4), which are special structures in DNA and RNA that play a crucial role in cells, have been associated with cancers and neurological diseases. A research team from City University of Hong Kong (CityU) recently ...
Biotechnology
Mar 21, 2024
0
0
Single-celled organisms, such as bacteria and archaea, have developed many ways to communicate with each other. For example, they might use tiny so-called extracellular vesicles (EVs)—membrane-enveloped packages smaller ...
Cell & Microbiology
Feb 27, 2024
0
7
During the reprogramming of somatic cells back into stem cells, gene regulation is controlled by pioneer transcription factors. These bind to the tightly packaged DNA in order to make it accessible.
Molecular & Computational biology
Feb 26, 2024
0
14
Klebsiella pneumoniae is one of the most common and most dangerous bacterial pathogens impacting humans, causing infections of the gastrointestinal tract, pneumonia, wound infections, and even blood poisoning.
Cell & Microbiology
Feb 20, 2024
0
23
Studying how rattlesnakes regulate their venom gives us important insight into how their genes are controlled. It also highlights the challenges in treating snakebites, according to new research in the journal Genome Biology ...
Plants & Animals
Jan 26, 2024
0
102
Human sex chromosomes originated from a pair of autosomes, the ordinary or non-sex chromosomes that contain the majority of our genome and come in identical pairs. That ancestral pair of autosomes diverged to become two different ...
Molecular & Computational biology
Dec 15, 2023
2
1197
Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...
Evolution
Nov 24, 2023
0
260
