IMP scientists from the lab of Alexander Stark show why certain activators—enhancers or cofactor proteins—activate specific promoters. The findings, which are now reported in the journal Nature, could have implications ...
Biotechnology
May 16, 2019
0
83
How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...
Molecular & Computational biology
May 2, 2019
0
91
Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat's unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the ...
Biotechnology
Mar 6, 2019
0
100
A team of engineers at the University of Delaware has developed a method to use CRISPR/Cas9 technology to set off a cascade of activities in cells, a phenomenon known as conditional gene regulation. Their method, described ...
Biochemistry
Dec 11, 2018
1
127
Transcription activator-like effector (TALE) proteins can be designed to bind to almost any selected DNA. Researchers now report that a TALE can displace another TALE protein from DNA in a highly polarized way – it can ...
Cell & Microbiology
Nov 26, 2018
0
27
Scientists once thought that humans must have 2 million genes to account for all our complexity. But since sequencing the human genome, researchers have learned that humans only have about 19,000 to 25,000 genes—not many ...
Evolution
Nov 21, 2018
0
121
Call it instinct, but something compels some animals to behave in certain ways, perhaps programs in their genes. Researchers have directly connected activities of genes with instinctive behavior in little male fish that make ...
Plants & Animals
Nov 14, 2018
0
42
Discovery of a gene that helps plants control their response to disease could aid efforts to develop crops that are resistant to infection, research suggests.
Biotechnology
Nov 2, 2018
0
111
Proteins are the building blocks of the cell. They do most of the work and are essential for the structure, function and dynamic regulation of the cell and body's tissues and organs. Proteins rarely work alone, they interact, ...
Cell & Microbiology
Oct 26, 2018
4
130
The microbial production of enzymes, chemicals and fuels could become more efficient and economical with a newly engineered system for controlling genes called "Jungle Express."
Cell & Microbiology
Sep 7, 2018
2
52
