News tagged with gene regulation
Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Aug 18, 2011 |
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A mystery solved: How genes are selectively silenced
Cells read only those genes which are needed at a given moment, while the others are chemically labeled and, thus, selectively turned off. Scientists at the German Cancer Research Center have now been the first to discover ...
Oct 18, 2010 |
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Researchers find that Sirtuin1 may boost memory and learning ability
The same molecular mechanism that increases life span through calorie restriction may help boost memory and brainpower, researchers at MIT's Picower Institute for Learning and Memory report in the July 11 ...
Medicine & Health / Neuroscience
Jul 11, 2010 |
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Mom's influence comes first: Maternal genes dominate in developing brains, while paternal ones lead in adult-hood
(PhysOrg.com) -- Genome-wide analysis of mice brains has found that maternally inherited genes are expressed preferentially in the developing brain, while the pattern shifts decisively in favor of paternal ...
Jul 08, 2010 |
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New genes implicated in high blood pressure
Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study, reporting ...
May 10, 2009 |
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New details about gene regulation explained
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase ...
May 21, 2012 |
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Scientists discover multiple gene switches in Salmonella, offer new ways to curb infection
Scientists have discovered multiple gene switches in Salmonella that offer new ways to curb human infection. The discovery of the mechanisms of gene regulation could lead to the development of antibiotics to reduce the le ...
Apr 23, 2012 |
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Scientists find a key to growth differences between species
The tiny, little-noticed jewel wasp may provide some answers as to how different species differ in size and shape. And that could lead to a better understanding of cell growth regulation, as well as the underlying ...
Feb 23, 2012 |
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Study provides new insights into an ancient mechanism of mammalian evolution
A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...
Jan 12, 2012 |
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Researchers identify new mechanism used by cells to reverse silenced genes
Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer -- suggesting the possibility of ...
Jun 30, 2011 |
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Key culprit identified in breast cancer metastasis
When doctors discover high concentrations of regulatory T cells in the tumors of breast cancer patients, the prognosis is often grim, though why exactly has long been unclear.
Feb 16, 2011 |
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'Linc-ing' a noncoding RNA to a central cellular pathway
The recent discovery of more than a thousand genes known as large intergenic non-coding RNAs (or "lincRNAs") opened up a new approach to understanding the function and organization of the genome. That surprising breakthrough ...
Jul 29, 2010 |
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'Runaway' development implicated in loss of function of the aging brain
The brain undergoes rapid growth and development in the early years of life and then degenerates as we progress into old age, yet little is known about the biological processes that distinguish brain development and aging. ...
Jul 19, 2010 |
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Genetic regulator opens new avenues to AIDS, immune system research
Researchers at Oregon State University and the California Institute of Technology have discovered that a genetic regulator which is critical to many life functions also plays a key role in the formation of "T cells," a type ...
Medicine & Health / HIV & AIDS
Jul 01, 2010 |
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Genetic research shows degeneration in ageing worm
Genetic research focusing on the soil nematode C. elegans has generated fundamental new insights into the way in which these tiny worms age. During the ageing process, the activity of the worm's genes gradually ...
May 28, 2010 |
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Regulation of gene expression
Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.