News tagged with gene regulation
Researchers find that Sirtuin1 may boost memory and learning ability
The same molecular mechanism that increases life span through calorie restriction may help boost memory and brainpower, researchers at MIT's Picower Institute for Learning and Memory report in the July 11 ...
Medicine & Health / Neuroscience
Jul 11, 2010 |
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A mystery solved: How genes are selectively silenced
Cells read only those genes which are needed at a given moment, while the others are chemically labeled and, thus, selectively turned off. Scientists at the German Cancer Research Center have now been the first to discover ...
Oct 18, 2010 |
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Mom's influence comes first: Maternal genes dominate in developing brains, while paternal ones lead in adult-hood
(PhysOrg.com) -- Genome-wide analysis of mice brains has found that maternally inherited genes are expressed preferentially in the developing brain, while the pattern shifts decisively in favor of paternal ...
Jul 08, 2010 |
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Protein shown to be natural inhibitor of aging in fruit fly model
Scientists at the University of California, San Diego School of Medicine, have identified a protein called Sestrin that serves as a natural inhibitor of aging and age-related pathologies in fruit flies. They ...
Medicine & Health / Medical research
Mar 04, 2010 |
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The food-energy cellular connection revealed
Our body's activity levels fall and rise to the beat of our internal drums—the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. Whereas ...
Medicine & Health / Medical research
Oct 15, 2009 |
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Researchers demonstrate that messenger RNA are lost in translation
Case Western Reserve University School of Medicine assistant professor in the Center for RNA Molecular Biology, Jeff Coller, Ph.D., and his team discovered that messenger RNA (mRNA) predominately degrade on ribosomes, fundamentally ...
Aug 23, 2009 |
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What makes us unique? Not genes so much as surrounding sequences
The key to human individuality may lie not in our genes, but in the sequences that surround and control them, according to new research by scientists at the Stanford University School of Medicine and Yale ...
Mar 18, 2010 |
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Toward new drugs that turn genes on and off
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
Jun 04, 2009 |
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Genetic research shows degeneration in ageing worm
Genetic research focusing on the soil nematode C. elegans has generated fundamental new insights into the way in which these tiny worms age. During the ageing process, the activity of the worm's genes gradually ...
May 28, 2010 |
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'Runaway' development implicated in loss of function of the aging brain
The brain undergoes rapid growth and development in the early years of life and then degenerates as we progress into old age, yet little is known about the biological processes that distinguish brain development and aging. ...
Jul 19, 2010 |
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Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Aug 18, 2011 |
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Rewiring of gene regulation across 300 million years of evolution
As published today in Science, researchers from Cambridge, Glasgow and Greece have discovered a remarkable amount of plasticity in how transcription factors, the proteins that bind to DNA to control the activation of gen ...
Apr 09, 2010 |
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Study provides new insights into an ancient mechanism of mammalian evolution
A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...
Jan 12, 2012 |
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Hairy secret of foraging plants discovered
(PhysOrg.com) -- The genes that control the hairy 'mining machine' that makes some plants better at finding nutrients in poor soils than others have been discovered by scientists from Oxford University and ...
Feb 18, 2010 |
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Modification of mutant huntingtin protein increases its clearance from brain cells
A new study has identified a potential strategy for removing the abnormal protein that causes Huntington's disease (HD) from brain cells, which could slow the progression of the devastating neurological disorder. In the ...
Medicine & Health / Medical research
Apr 02, 2009 |
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Regulation of gene expression
Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.