News tagged with gene regulation
New details about gene regulation explained
(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase ...
May 21, 2012 |
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Three periods of innovation in gene regulation occurred during the evolution of vertebrate animals: study
Over the past 530 million years, the vertebrate lineage branched out from a primitive jawless fish wriggling through Cambrian seas to encompass all the diverse forms of fish, birds, reptiles, amphibians, and mammals. Now ...
Aug 18, 2011 |
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A mystery solved: How genes are selectively silenced
Cells read only those genes which are needed at a given moment, while the others are chemically labeled and, thus, selectively turned off. Scientists at the German Cancer Research Center have now been the first to discover ...
Oct 18, 2010 |
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Scientists find a key to growth differences between species
The tiny, little-noticed jewel wasp may provide some answers as to how different species differ in size and shape. And that could lead to a better understanding of cell growth regulation, as well as the underlying ...
Feb 23, 2012 |
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Researchers find that Sirtuin1 may boost memory and learning ability
The same molecular mechanism that increases life span through calorie restriction may help boost memory and brainpower, researchers at MIT's Picower Institute for Learning and Memory report in the July 11 ...
Medicine & Health / Neuroscience
Jul 11, 2010 |
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Scientists discover multiple gene switches in Salmonella, offer new ways to curb infection
Scientists have discovered multiple gene switches in Salmonella that offer new ways to curb human infection. The discovery of the mechanisms of gene regulation could lead to the development of antibiotics to reduce the le ...
Apr 23, 2012 |
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Mom's influence comes first: Maternal genes dominate in developing brains, while paternal ones lead in adult-hood
(PhysOrg.com) -- Genome-wide analysis of mice brains has found that maternally inherited genes are expressed preferentially in the developing brain, while the pattern shifts decisively in favor of paternal ...
Jul 08, 2010 |
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Study provides new insights into an ancient mechanism of mammalian evolution
A team of geneticists and computational biologists in the UK today reveal how an ancient mechanism is involved in gene control and continues to drive genome evolution. The new study is published in the journal ...
Jan 12, 2012 |
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Hairy secret of foraging plants discovered
(PhysOrg.com) -- The genes that control the hairy 'mining machine' that makes some plants better at finding nutrients in poor soils than others have been discovered by scientists from Oxford University and ...
Feb 18, 2010 |
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New genes implicated in high blood pressure
Researchers at the Johns Hopkins University School of Medicine, along with an international team of collaborators, have identified common genetic changes associated with blood pressure and hypertension. The study, reporting ...
May 10, 2009 |
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Key culprit identified in breast cancer metastasis
When doctors discover high concentrations of regulatory T cells in the tumors of breast cancer patients, the prognosis is often grim, though why exactly has long been unclear.
Feb 16, 2011 |
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Researchers identify new mechanism used by cells to reverse silenced genes
Scientists at Fox Chase Cancer Center have discovered a new mechanism used by cells in the body to turn on silenced genes. This process is critical in preventing the development of cancer -- suggesting the possibility of ...
Jun 30, 2011 |
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MicroRNA network study implicates rewired interactions in cancer
Genes interact in complex networks that govern cellular processes, much like people connect a social network through relationships. Researchers are now discovering how biological networks change and are rewired in cancer. ...
May 02, 2010 |
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What makes us unique? Not genes so much as surrounding sequences
The key to human individuality may lie not in our genes, but in the sequences that surround and control them, according to new research by scientists at the Stanford University School of Medicine and Yale ...
Mar 18, 2010 |
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Protein shown to be natural inhibitor of aging in fruit fly model
Scientists at the University of California, San Diego School of Medicine, have identified a protein called Sestrin that serves as a natural inhibitor of aging and age-related pathologies in fruit flies. They ...
Medicine & Health / Medical research
Mar 04, 2010 |
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Regulation of gene expression
Gene modulation redirects here. For information on therapeutic regulation of gene expression, see therapeutic gene modulation.
Regulation of gene expression (or gene regulation) includes the processes that cells and viruses use to turn the information in genes into gene products. Although a functional gene product may be an RNA or a protein, the majority of known mechanisms regulate protein coding genes. Any step of the gene's expression may be modulated, from DNA-RNA transcription to the post-translational modification of a protein.
Gene regulation is essential for viruses, prokaryotes and eukaryotes as it increases the versatility and adaptability of an organism by allowing the cell to express protein when needed. The first discovered example of a gene regulation system was the lac operon, discovered by Jacques Monod, in which protein involved in lactose metabolism are expressed by E.coli only in the presence of lactose and absence of glucose.
Furthermore, gene regulation drives the processes of cellular differentiation and morphogenesis, leading to the creation of different cell types in multicellular organisms where the different types of cells may possess different gene expression profiles though they all possess the same genome sequence.
For more information about Regulation of gene expression, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.