Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

Project reveals genome of celebrity cat Lil BUB

Lil BUB has drawn millions of followers across the internet for her cute appearance. Behind the celebrity cat's unique features is a combination of two rare genetic variants, three molecular biologists from Germany and the ...

Genome structure of malaria parasites linked to virulence

An international research team led by scientists at the University of California, Riverside, and the La Jolla Institute for Immunology has found that malaria parasite genomes are shaped by parasite-specific gene families, ...

Time to step inside your DNA

Researchers at the MRC Weatherall Institute of Molecular Medicine (MRC WIMM) have developed technology that allows scientists to explore the complex 3-D structure of DNA in Virtual Reality. In a newly published pre-print, ...

CRISPR method for conditional gene regulation

A team of engineers at the University of Delaware has developed a method to use CRISPR/Cas9 technology to set off a cascade of activities in cells, a phenomenon known as conditional gene regulation. Their method, described ...

What makes vertebrates special? We can learn from lancelets

Scientists once thought that humans must have 2 million genes to account for all our complexity. But since sequencing the human genome, researchers have learned that humans only have about 19,000 to 25,000 genes—not many ...

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