The making of 'Fancy Mouse'

For the past few hundred years, the colorful hair and unique patterns of the so-called "Fancy Mouse" have made them the stars of pet shows in Japan and beyond. Now, scientists have finally revealed the true cause of the genetic ...

Novel mechanism of inheritance detected

Non-Mendelian, oligogenic inheritance could be an unrecognized and important element for occurrence of hereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and ...

Neutral evolution shapes lifespan and aging

Different African killifish species vary extensively in their lifespans—from just a few months to several years. Scientists from the Max Planck Institute for Biology of Ageing in Cologne investigated how different lifespans ...

Researchers create most complete model of complex protein machinery

Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...

Cryptic mutation is cautionary tale for crop gene editing

Even in this "age of the genome," much about genes remains shrouded in mystery. This is especially true for "cryptic mutations"—mutated genes that are hidden, and have unexpected effects on traits that are only revealed ...

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