Finding meaning in gene expression 'noise'

Static models of gene regulation networks are inevitably oversimplified, indicating how one gene specifically switches certain target genes on while turning others off. However, the reality is much more dynamic and thus noisier. ...

Extinct fossils reveal their genetic pattern

Researchers have provided a glimpse at genetic expression in long-extinct fossil dinosaurs. This new insight comes from the discovery of a correlation between the genetic patterning observed in today's chickens and crocodiles, ...

Google-style ranking used to describe gene connectivity

Using the technique known as "Gene Rank" (GR), Dartmouth's Norris Cotton Cancer Center investigator Eugene Demidenko, PhD, captured and described a new characterization of gene connectivity in "Microarray Enriched Gene Rank," ...

Deep learning applied to drug discovery and repurposing

In a recently accepted manuscript titled "Deep learning applications for predicting pharmacological properties of drugs and drug repurposing using transcriptomic data", scientists from Insilico Medicine, Inc located at the ...

A one-stop shop for analyzing algal genomes

Interested in the genomes of algae? You now have one place where you can browse the genetic blueprints of these photosynthetic organisms. PhycoCosm is one of the largest data repositories of its kind, with an interactive ...

New method melds data to make a 3-D map of cells' activities

Just as it's hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell's environment. To solve that problem, researchers ...

Mathematics meets biology to uncover unexpected biorhythms

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles. The method, published in the journal PLOS ONE, assessed the periodicity ...

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