A new paper in Cell Systems explores the importance of using multiple data types in drug discovery. The paper screens more than 1,000 drugs tested in six doses and demonstrates that gene expression and cell morphology provide ...
Cell & Microbiology
Oct 24, 2022
0
4
A team of researchers affiliated with multiple institutions in the U.S., has found that dolphins living in the area where the Deepwater Horizon oil spill occurred have experienced changes in gene activity. In their paper ...
Medical and life science researchers will benefit from the most comprehensive atlas yet of genetic data on zebrafish, newly published research suggests.
Biotechnology
Jul 4, 2022
0
399
In almost every human cell, 2 meters of DNA has to fit within a nucleus that is just 8 millionths of a meter wide. Like wool around a spool, the extreme space challenge requires DNA to wrap around structural proteins called ...
Evolution
Jun 9, 2022
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47
Just as it's hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell's environment. To solve that problem, researchers ...
Cell & Microbiology
May 16, 2022
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126
In human chromosomes, DNA is coated by proteins to form an exceedingly long beaded string. This "string" is folded into numerous loops, which are believed to help cells control gene expression and facilitate DNA repair, among ...
Cell & Microbiology
Apr 14, 2022
0
275
Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos. This new capability is helping biologists understand ...
Molecular & Computational biology
Oct 4, 2021
0
247
A good way to find out what a cell is doing—whether it is growing out of control as in cancers, or is under the control of an invading virus, or is simply going about the routine business of a healthy cell—is to look ...
Biotechnology
Apr 5, 2021
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483
Gene expression is a highly regulated process that involves several steps. These include transcription of DNA instructions into RNA, removal of non-coding segments from the RNA message, and its subsequent translation into ...
Biotechnology
Feb 5, 2021
0
46
In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately ...
Biotechnology
Jan 18, 2021
0
45
