News tagged with gene activity

Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, known as heterochromatin. ...

dateSep 25, 2012 in Cell & Microbiology
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Functional genomics gets tiny

A little more than a decade ago, researchers discovered an ancient mechanism that cells use to silence genes. Like a dimmer switch turning down a light, RNA interference (RNAi) dials down gene activity in simple organisms ...

dateMay 17, 2012 in Cell & Microbiology
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With genomes, bigger may really be better

Biologists analyzing DNA in search of the molecular underpinnings of life have consistently favored species with small genomes, which are cheaper to sequence and lack the repetitive "junk" that clutters bigger genomes. But ...

dateMar 04, 2009 in Cell & Microbiology
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Activating ALC1: With a little help from friends

Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well ...

dateNov 29, 2012 in Biochemistry
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