News tagged with gene activation

Making and breaking heterochromatin

To fit the two-meter long DNA molecule into a cell nucleus that is only a few thousandths of a millimetre in size, long sections of the DNA must be strongly compacted. Epigenetic marks maintain these sections, ...

dateSep 25, 2012 in Cell & Microbiology
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Life's tiniest architects pinpointed

If a genome is the blueprint for life, then the chief architects are tiny slices of genetic material that orchestrate how we are assembled and function, Yale School of Medicine researchers report Feb. 21 in the journal Developmental Ce ...

dateFeb 21, 2013 in Cell & Microbiology
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The TALE of new tools to study gene regulation

In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...

dateJul 01, 2013 in Biotechnology
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Functional genomics gets tiny

A little more than a decade ago, researchers discovered an ancient mechanism that cells use to silence genes. Like a dimmer switch turning down a light, RNA interference (RNAi) dials down gene activity in ...

dateMay 17, 2012 in Cell & Microbiology
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