News tagged with estrogen receptor
Protein structures give disease clues
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules ...
Feb 01, 2012 |
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New sensors streamline detection of estrogenic compounds
Researchers have engineered new sensors that fluoresce in the presence of compounds that interact with estrogen receptors in human cells. The sensors detect natural or human-made substances that alter estrogenic signaling ...
Aug 25, 2011 |
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The unexpected action of bisphenol A on the inner ear of certain vertebrates
Bisphenol A, whose impact on reproduction and development is the subject of numerous studies, induces anomalies in the inner ear of embryos of certain vertebrates. This new, completely unsuspected effect has ...
Mar 16, 2011 |
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Liver, dietary proteins key in fertility
When you think about organs with an important role in reproduction, the liver most likely doesn't spring to mind. But a new report in the February issue of Cell Metabolism, a Cell Press publication, shows that estrogen recept ...
Medicine & Health / Medical research
Feb 01, 2011 |
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Anti-estrogen medication reduces risk of dying from lung cancer
A new study has found that tamoxifen, an anti-estrogen breast cancer medication, may reduce an individual's risk of death from lung cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer ...
Jan 24, 2011 |
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Body fat distribution associated with a higher risk of ER-negative breast cancer
Body fat distribution does not play an important role in the incidence of every subtype of premenopausal breast cancer, but is associated with an increased risk for estrogen receptor (ER)–negative breast cancer, according ...
Dec 15, 2010 |
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Too much of a good thing: Important mechanism in hormone-sensitive breast cancer uncovered
In two out of three breast tumors, extraordinarily high levels of the estrogen receptor ERalpha are found. Scientists of the German Cancer Research Center have now uncovered a mechanism which causes this overproduction. ...
Nov 23, 2010 |
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Why estrogen makes you smarter
Estrogen is an elixir for the brain, sharpening mental performance in humans and animals and showing promise as a treatment for disorders of the brain such as Alzheimer's disease and schizophrenia. But long-term estrogen ...
Medicine & Health / Neuroscience
Nov 17, 2010 |
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Liquorice root may protect brain cells
A neuroscientist at the University of South Carolina is conducting research on a compound found in liquorice root that could prevent or slow down the cell death associated with neurodegenerative diseases such as Alzheimer’s ...
Medicine & Health / Neuroscience
Nov 12, 2010 |
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Lasofoxifene reduces breast cancer risk in postmenopausal osteoporotic women
Lasofoxifene statistically reduced the overall risk of breast cancer, as well as ER positive invasive breast cancer in postmenopausal women with low bone density, according to a study published online in The Journal of th ...
Nov 04, 2010 |
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Clue to unusual drug-resistant breast cancers found
Researchers at the University of Illinois at Chicago College of Medicine have found how gene expression that may contribute to drug resistance is ramped up in unusual types of breast tumors. Their findings may offer new therapy ...
Oct 08, 2010 |
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Oral contraceptive use associated with increased risk of breast cancer
Investigators from the Slone Epidemiology Center at Boston University School of Medicine (BUSM) have reported that African American women who use oral contraceptives have a greater likelihood of developing breast cancer than ...
Aug 03, 2010 |
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Genetic risk score associated with breast cancer risk; predictive of type of disease
Women with higher risk scores that consisted of having certain genetic variants most strongly linked to breast cancer had an associated higher risk of breast cancer, with these scores also highly predictive of estrogen receptor-positive ...
Jul 27, 2010 |
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New System Boosts Yield of Isoflavonoids That Bind Estrogen Receptors
(PhysOrg.com) -- The promise of new pharmaceutical treatments from a class of powerful plant compounds called isoflavonoids has remained unfulfilled because of problems biosynthesizing sufficient quantities of the compound ...
Medicine & Health / Medical research
May 14, 2010 |
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Slight changes in 2 key genes appear to launch breast cancer development
Researchers at Georgetown Lombard Comprehensive Cancer Center have been able to show, in mice, how just a little adjustment in the expression of two common genes can promote the kind of cellular changes that led to breast ...
May 13, 2010 |
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Estrogen receptor
Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol (estrogen). Two types of estrogen receptor exist: ER which is a member of the nuclear hormone family of intracellular receptors and the estrogen G protein coupled receptor GPR30 (GPER), which is a G-protein coupled receptor. This article refers to the nuclear hormone receptor ER.
The main function of the estrogen receptor is as a DNA binding transcription factor that regulates gene expression. However, the estrogen receptor has additional functions independent of DNA binding.
For more information about Estrogen receptor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
