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Not all cellular reprogramming is created equal

Tweaking the levels of factors used during the reprogramming of adult cells into induced pluriopotent stem (iPS) cells greatly affects the quality of the resulting iPS cells, according to Whitehead Institute researchers.

Biology / Cell & Microbiology

created Dec 01, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Human embryonic stem cells and reprogrammed cells virtually identical

Human embryonic stem (ES) cells and adult cells reprogrammed to an embryonic stem cell-like state—so-called induced pluripotent stem or iPS cells—exhibit very few differences in their gene expression signatures and are nearly ...

Biology / Cell & Microbiology

created Aug 05, 2010 | popularity 4.9 / 5 (7) | comments 1 | with audio podcast

Scientists discover ancient viral invasion that shaped human genome

Scientists at the Genome Institute of Singapore (GIS) and their colleagues from the National University of Singapore, Nanyang Technological University, Duke-NUS Graduate Medical School and Princeton University have recently ...

Medicine & Health / Genetics

created Jun 07, 2010 | popularity 4.7 / 5 (16) | comments 6 | with audio podcast

Researchers find gene to explain mouse embryonic stem cell immortality

Researchers at the National Institute on Aging (NIA), part of the National Institutes of Health, have discovered a key to embryonic stem (ES) cell rejuvenation in a gene -- Zscan4 -- as reported in the March 24, 2010, online ...

Biology / Cell & Microbiology

created Mar 24, 2010 | popularity 5 / 5 (8) | comments 3 | with audio podcast

Replacing faulty neurons

Researchers from the RIKEN Center for Developmental Biology, Kobe, have shown that neurons called Purkinje cells can not only be generated from embryonic stem (ES) cells, but can also become fully integrated ...

Medicine & Health / Neuroscience

created Nov 05, 2010 | popularity 4 / 5 (2) | comments 0