News tagged with epigenome
Epigenome
Epigenome is equivalent to genome in epigenetics. Epigenetics is one of the current topics in cancer research drawing active research. Human tumors undergo a major disruption of DNA methylation and histone modification patterns. The aberrant epigenetic landscape of the cancer cell is characterized by a massive genomic hypomethylation, CpG island promoter hypermethylation of tumor suppressor genes, an altered histone code for critical genes and a global loss of monoacetylated and trimethylated histone H4.
Much of the subject matter is not yet fully understood. Some people have suggested a Human Epigenome Project.[citation needed]
For more information about Epigenome, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
Study reveals dynamic changes in gene regulation in human stem cells
A team led by scientists at The Scripps Research Institute and the University of California (UC) San Diego has discovered a new type of dynamic change in human stem cells.
May 03, 2012 |
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In the case of DNA, the package can be as important as its contents: study
(PhysOrg.com) -- In 2003, the year a complete draft of the human genome was released, the U.S. National Human Genome Research Institute launched the ENCODE project (ENCyclopedia of DNA Elements), to develop ...
Jan 12, 2011 |
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JAMA commentary: Time to rethink causes, possible treatments of mental disorders
It is time to reassess mental disorders, recognizing that these are disorders of brain circuits likely caused by development processes, according to a commentary in the May 19 issue of JAMA, a theme issue on mental health ...
Medicine & Health / Psychology & Psychiatry
May 18, 2010 |
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Pluripotent and differentiated human cells reside in decidedly different epigenomic landscapes
Human embryonic stem cells (hESCs) possess remarkable properties of self-renewal and pluripotency, the ability to become almost any kind of cell within the body. And yet they share the same genome or set of genes with lineage-committed ...
May 06, 2010 |
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Biochemists take a bead on gene-controlling code
(PhysOrg.com) -- DNA may provide the blueprint for life, but scientists are learning more about the role of a chemical code that governs the way that blueprint is read.
Mar 02, 2010 |
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What drives our genes? Researchers map the first complete human epigenome
Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated. Now, researchers ...
Oct 14, 2009 |
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