The epigenetics of life at 12,000 feet

Humans inhabit an incredible range of environments across the globe, from arid deserts to frozen tundra, tropical rainforests, and some of the highest peaks on Earth. Indigenous populations that have lived in these extreme ...

In situ sequencing of the fully structured genome

There is a sense in which the information encoded in a gene sequence can be represented by two bits per base pair location. The reality, however, is that this is far from a complete description. Although many academically ...

How epigenetic switches control gene expression

Scientists at Tokyo Institute of Technology have deciphered how to quantitatively assess the effects of specific epigenetic changes on the rate of transcription by developing a mathematical model. Using their method, they ...

Yeast study yields insights into longstanding evolution debate

In the past two decades, researchers have shown that biological traits in both species and individual cells can be shaped by the environment and inherited even without gene mutations, an outcome that contradicts one of the ...

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