After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at the Department of Energy's Oak Ridge National Laboratory are now ...
Biochemistry
Aug 14, 2023
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65
Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes. These enzymes are growing increasingly common, appearing worldwide ...
Biotechnology
Aug 14, 2023
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8
Chemotherapy is a mainstay of cancer treatment. While effective, this therapy indiscriminately kills rapidly dividing cells—cancerous or otherwise—so patients frequently experience severe side effects, ultimately limiting ...
Bio & Medicine
Aug 9, 2023
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18
Industrial biocatalysis with enzymes is deemed to be a "game changer" in the development of a sustainable chemical industry. Enzymes can be used to synthesize an impressive range of complex molecules, including pharmaceutical ...
Biochemistry
Aug 9, 2023
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64
A new study reveals an important discovery in the realm of nanomachines within living systems. Prof. Sason Shaik from the Hebrew University of Jerusalem and Dr. Kshatresh Dutta Dubey from Shiv Nadar University, conducted ...
Bio & Medicine
Aug 7, 2023
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58
Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing—the production of fuels, plastics, and valuable chemicals from ...
Biochemistry
Jul 31, 2023
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15
Enzymes play a key role in cellular metabolic processes. To enable the quantitative assessment of these processes, researchers need to know the so-called "turnover number" (for short: kcat) of the enzymes. In the journal ...
Cell & Microbiology
Jul 24, 2023
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2
Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme activity. The key role is played ...
Cell & Microbiology
Jul 21, 2023
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48
One of the central challenges for synthetic chemists is to impose control over free radicals. Highly reactive molecules with an unpaired electron, free radicals, may be familiar to you; these are the type of molecules we ...
Biochemistry
Jul 21, 2023
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184
University at Buffalo researchers have identified for the first time an enzyme in the foxglove plant that is responsible for the production of compounds needed to make the heart failure drug digoxin.
Plants & Animals
Jul 17, 2023
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